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Inconsistent Report...
Inconsistent Reporting Between Meta-analysis Protocol and Publication – A Cross-Sectional Study
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- Falk Delgado, Alberto (författare)
- Karolinska Institutet,Uppsala universitet,Plastikkirurgi
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- Falk Delgado, Anna (författare)
- Karolinska Institute, Department of Clinical Neuroscience
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(creator_code:org_t)
- Anticancer Research USA Inc. 2017
- 2017
- Engelska.
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Ingår i: Anticancer Research. - : Anticancer Research USA Inc.. - 0250-7005 .- 1791-7530. ; 37:9, s. 5101-5107
- Relaterad länk:
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http://ar.iiarjourna...
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https://urn.kb.se/re...
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https://doi.org/10.2...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Inconsistent reporting in published meta-analyses compared to registered protocol are poorly understood. The aim of the study was to assess inconsistencies between registered protocols and published reports among oncology drug meta-analyses.Materials and Methods: A cross-sectional study was performed including oncology drug meta-analyses published between January 1st and November 14th 2016 with a published protocol. Two investigators extracted data on: selection criteria, outcome(s) and statistical plan in protocol and manuscript, plus self-acknowledgement of inconsistent reporting between protocol and publication.Results: Protocol registration was present in 19% (23/119) of all oncology drug meta-analyses. In meta-analyses with protocol (n= 23), 70% (16/23) had issues with inconsistent reporting between protocol and published report concerning; inclusion criteria, comparator group, intervention, outcome (PICO) or statistical analysis. Self-acknowledgement of changes between protocol and publication was found in 50% (8/16).Conclusion: In meta-analyses with protocol, discrepancies between registered protocols and publications are frequent.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Meta-analysis protocol
- inconsistent reporting
- published report
- trial registration
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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