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Use of copeptin for...
Use of copeptin for rapid rule-out of acute myocardial infarction
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- Mueller, Christian (author)
- Univ Hosp Basel, Dept Cardiol, Basel, Switzerland; Univ Hosp Basel, Cardiovasc Res Inst Basel, Basel, Switzerland
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- Möckel, Martin (author)
- Charite Univ Med Berlin, Div Emergency Med, Berlin, Germany
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- Giannitsis, Evangelos (author)
- Heidelberg Univ, Med Klin 3, Heidelberg, Germany
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- Huber, Kurt (author)
- Wilhelminen Hosp, Dept Med Cardiol & Intens Care Med, Vienna, Austria
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- Mair, Johannes (author)
- Innsbruck Med Univ, Dept Internal Med Cardiol & Angiol 3, Innsbruck, Austria
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- Plebani, Mario (author)
- Univ Hosp Padova, Dept Lab Med, Padua, Italy
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- Thygesen, Kristian (author)
- Aarhus Univ Hosp, Dept Cardiol, Aarhus, Denmark
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- Jaffe, Allan S (author)
- Mayo Clin, Rochester, MN USA; Med Sch, Rochester, MN USA
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- Lindahl, Bertil, 1957- (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Uppsala kliniska forskningscentrum (UCR),UCR
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(creator_code:org_t)
- 2017-06-08
- 2018
- English.
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In: European Heart Journal. - : Oxford University Press (OUP). - 2048-8726 .- 2048-8734. ; 7:6, s. 570-576
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Copeptin is currently understood as a quantitative marker of endogenous stress. It rises rapidly in multiple acute disorders including acute myocardial infarction. As a single variable, it has only modest diagnostic accuracy for acute myocardial infarction. However, the use of copeptin within a dual-marker strategy together with conventional cardiac troponin increases the diagnostic accuracy and particularly the negative predictive value of cardiac troponin alone for acute myocardial infarction. The rapid rule-out of acute myocardial infarction is the only application in acute cardiac care mature enough to merit consideration for routine clinical care. However, the dual-marker approach seems to provide only very small incremental value when used in combination with sensitive or high-sensitivity cardiac troponin assays. This review aims to update and educate regarding the potential and the procedural details, as well as the caveats and challenges of using copeptin in clinical practice.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Acute myocardial infarction
- diagnosis
- rule-out
Publication and Content Type
- ref (subject category)
- art (subject category)
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Mueller, Christi ...
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Möckel, Martin
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Giannitsis, Evan ...
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Huber, Kurt
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Mair, Johannes
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Plebani, Mario
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Thygesen, Kristi ...
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Jaffe, Allan S
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Lindahl, Bertil, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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European Heart J ...
- By the university
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Uppsala University