Search: id:"swepub:oai:DiVA.org:uu-342517" > Antibodies against ...
Fältnamn | Indikatorer | Metadata |
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000 | 03623naa a2200505 4500 | |
001 | oai:DiVA.org:uu-342517 | |
003 | SwePub | |
008 | 180221s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3425172 URI |
024 | 7 | a https://doi.org/10.3389/fimmu.2017.015952 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Ernst, Diana4 aut |
245 | 1 0 | a Antibodies against MYC-Associated Zinc Finger Protein :b An Independent Marker in Acute Coronary Syndrome? |
264 | c 2017-11-21 | |
264 | 1 | b Frontiers Media SA,c 2017 |
338 | a electronic2 rdacarrier | |
520 | a Introduction: Atherosclerosis is considered the pathophysiology underlying cardiovascular (CVD), cerebrovascular, and peripheral vascular diseases. Evidence supporting an autoimmune component is emerging, with imaging studies correlating MYC-associated zinc finger protein antibody (MAZ-Ab) optical density (OD) with plaque activity. This study compares MAZ-Ab OD on ELISA testing among patients presenting with acute coronary syndromes (ACSs) to healthy controls and investigates the association of MAZ-Ab to traditional CVD risk factors.Methods: Patients admitted with ACSs between August 2007 and July 2011 were included. Serum samples taken at presentation were retrospectively tested for MAZ-Ab and compared with serum from healthy volunteers with no CVD risk factors. Large-scale assessment of post-ACS prognostic relevance was performed using the established PLATO cohort.Results: = 0.436).Conclusion: MAZ-Ab OD was higher or all ACS phenotypes compared with controls. Given current understanding of MAZ-Ab function, these findings support an autoimmune component to CVD independent of conventional risk factors and indeed the extent of end-organ damage. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng |
653 | a MYC-associated zinc finger protein | |
653 | a acute coronary syndrome | |
653 | a antibodies | |
653 | a atherosclerosis | |
653 | a cardiac risk factor | |
700 | 1 | a Widera, Christian4 aut |
700 | 1 | a Baerlecken, Niklas T4 aut |
700 | 1 | a Schlumberger, Wolfgang4 aut |
700 | 1 | a Daehnrich, Cornelia4 aut |
700 | 1 | a Schmidt, Reinhold E4 aut |
700 | 1 | a Gabrysch, Katjau Uppsala universitet,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)kattr302 |
700 | 1 | a Wallentin, Lars,d 1943-u Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)larswall |
700 | 1 | a Witte, Torsten4 aut |
710 | 2 | a Uppsala universitetb Uppsala kliniska forskningscentrum (UCR)4 org |
773 | 0 | t Frontiers in Immunologyd : Frontiers Media SAg 8q 8x 1664-3224 |
856 | 4 | u https://doi.org/10.3389/fimmu.2017.01595y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1184541/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://www.frontiersin.org/articles/10.3389/fimmu.2017.01595/pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-342517 |
856 | 4 8 | u https://doi.org/10.3389/fimmu.2017.01595 |
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