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Sökning: id:"swepub:oai:DiVA.org:uu-350613" > A comprehensive gen...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008504naa a2200865 4500
001oai:DiVA.org:uu-350613
003SwePub
008180523s2018 | |||||||||||000 ||eng|
009oai:DiVA.org:nrm-3133
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3506132 URI
024a https://doi.org/10.1073/pnas.17205541152 DOI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-31332 URI
040 a (SwePub)uud (SwePub)nrm
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Palkopoulou, Eleftheriau Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut
2451 0a A comprehensive genomic history of extinct and living elephants
264 c 2018-02-26
264 1b NATL ACAD SCIENCES,c 2018
338 a print2 rdacarrier
520 a Elephantids are the world's most iconic megafaunal family, yet there is no comprehensive genomic assessment of their relationships. We report a total of 14 genomes, including 2 from the American mastodon, which is an extinct elephantid relative, and 12 spanning all three extant and three extinct elephantid species including an similar to 120,000-y-old straight-tusked elephant, a Columbian mammoth, and woolly mammoths. Earlier genetic studies modeled elephantid evolution via simple bifurcating trees, but here we show that interspecies hybridization has been a recurrent feature of elephantid evolution. We found that the genetic makeup of the straight-tusked elephant, previously placed as a sister group to African forest elephants based on lower coverage data, in fact comprises three major components. Most of the straight-tusked elephant's ancestry derives from a lineage related to the ancestor of African elephants while its remaining ancestry consists of a large contribution from a lineage related to forest elephants and another related to mammoths. Columbian and woolly mammoths also showed evidence of interbreeding, likely following a latitudinal cline across North America. While hybridization events have shaped elephantid history in profound ways, isolation also appears to have played an important role. Our data reveal nearly complete isolation between the ancestors of the African forest and savanna elephants for similar to 500,000 y, providing compelling justification for the conservation of forest and savanna elephants as separate species.
650 7a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng
650 7a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng
653 a paleogenomics
653 a elephantid evolution
653 a mammoth
653 a admixture
653 a species divergence
653 a Diversity of life
700a Lipson, Marku Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.4 aut
700a Mallick, Swapanu Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut
700a Nielsen, Svendu Aarhus Univ, Bioinformat Res Ctr, DK-8000 Aarhus, Denmark.4 aut
700a Rohland, Nadinu Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.4 aut
700a Baleka, Sinau Univ Potsdam, Unit Gen Zool Evolutionary Adapt Genom, Inst Biochem & Biol, Fac Math & Life Sci, D-14476 Potsdam, Germany.4 aut
700a Karpinski, Emilu McMaster Univ, McMaster Ancient DNA Ctr, Dept Anthropol, Hamilton, ON L8S 4L9, Canada.;McMaster Univ, Dept Biol, Hamilton, ON L8S 4K1, Canada.;McMaster Univ, Dept Biochem, Hamilton, ON L8S 4L8, Canada.;McMaster Univ, Michael G DeGroote Inst Infect Dis Res, Hamilton, ON L8S 4L8, Canada.4 aut
700a Ivancevici, Atma M.u Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut
700a To, Thu-Hien4 aut
700a Kortschak, Danielu Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut
700a Raison, Joy M.u Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut
700a Qu, Zhipengu Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut
700a Chin, Tat-Junu Univ Adelaide, Sch Comp Sci, Adelaide, SA 5005, Australia.4 aut
700a Alt, Kurt W.u Danube Private Univ, Ctr Nat & Cultural Human Hist, A-3500 Krems, Austria.;Univ Basel, Univ Basel Hosp, Dept Biomed Engn, CH-4123 Basel, Switzerland.;Univ Basel, Integrat Prehist & Archaeol Sci, CH-4051 Basel, Switzerland.4 aut
700a Claesson, Stefanu Inst Maritime Hist, Tall Timbers, MD 20690 USA.4 aut
700a Dalén, Loveu Naturhistoriska riksmuseet,Enheten för bioinformatik och genetik4 aut0 (Swepub:nrm)lovedale
700a MacPhee, Ross D. E.u Amer Museum Nat Hist, Div Vertebrate Zool Mammal, New York, NY 10024 USA.4 aut
700a Meller, Haraldu State Off Heritage Management & Archaeol, D-06114 Halle, Saale, Germany.4 aut
700a Rocar, Alfred L.u Univ Illinois, Dept Anim Sci, Urbana, IL 61801 USA.;Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USA.4 aut
700a Ryder, Oliver A.u San Diego Zoo, Inst Conservat Res, Escondido, CA 92027 USA.4 aut
700a Heiman, Davidu Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut
700a Young, Sarahu Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut
700a Breen, Matthewu North Carolina State Univ, Coll Vet Med, Dept Mol Biomed Sci, Raleigh, NC 27607 USA.4 aut
700a Williams, Christinau North Carolina State Univ, Coll Vet Med, Dept Mol Biomed Sci, Raleigh, NC 27607 USA.4 aut
700a Aken, Bronwen L.u European Bioinformat Inst, European Mol Biol Lab, Cambridge CB10 1SD, England.;Wellcome Sanger Inst, Cambridge CB10 1SD, England.4 aut
700a Ruffier, Magaliu European Bioinformat Inst, European Mol Biol Lab, Cambridge CB10 1SD, England.;Wellcome Sanger Inst, Cambridge CB10 1SD, England.4 aut
700a Karlsson, Elinoru Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Univ Massachusetts, Sch Med, Program Bioinformat & Integrat Biol, Worcester, MA 01655 USA.4 aut
700a Johnson, Jeremyu Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut
700a Di Palma, Federicau Earlham Inst, Norwich NR4 7UZ, Norfolk, England.4 aut
700a Alfoldi, Jessicau Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut
700a Adelsoni, David L.u Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut
700a Mailund, Thomasu Aarhus Univ, Bioinformat Res Ctr, DK-8000 Aarhus, Denmark.4 aut
700a Munch, Kasperu Aarhus Univ, Bioinformat Res Ctr, DK-8000 Aarhus, Denmark.4 aut
700a Lindblad-Toh, Kerstinu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab,Broad Inst MIT & Harvard, Cambridge, MA 02142 USA4 aut0 (Swepub:uu)kerli865
700a Hofreiter, Michaelu Univ Potsdam, Unit Gen Zool Evolutionary Adapt Genom, Inst Biochem & Biol, Fac Math & Life Sci, D-14476 Potsdam, Germany.4 aut
700a Poinar, Hendriku McMaster Univ, McMaster Ancient DNA Ctr, Dept Anthropol, Hamilton, ON L8S 4L9, Canada.;McMaster Univ, Dept Biol, Hamilton, ON L8S 4K1, Canada.;McMaster Univ, Dept Biochem, Hamilton, ON L8S 4L8, Canada.;McMaster Univ, Michael G DeGroote Inst Infect Dis Res, Hamilton, ON L8S 4L8, Canada.4 aut
700a Reich, Davidu Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Harvard Med Sch, Howard Hughes Med Inst, Boston, MA 02115 USA.4 aut
710a Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.b Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.4 org
773t Proceedings of the National Academy of Sciences of the United States of Americad : NATL ACAD SCIENCESg 115:11, s. E2566-E2574q 115:11<E2566-E2574x 0027-8424x 1091-6490
856u https://www.pnas.org/content/pnas/115/11/E2566.full.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-350613
8564 8u https://doi.org/10.1073/pnas.1720554115
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-3133

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