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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02921naa a2200409 4500 | |
| 001 | oai:DiVA.org:uu-358051 | |
| 003 | SwePub | |
| 008 | 180823s2018 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3580512 URI |
| 024 | 7 | a https://doi.org/10.1016/bs.mcb.2018.05.0102 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a kap2 swepub-publicationtype |
| 100 | 1 | a Kim, Anna Au Uppsala universitet,Mikrosystemteknik,Stanford University, USA; University of California, Santa Barbara, USA4 aut0 (Swepub:uu)annki239 |
| 245 | 1 0 | a Microfluidics for mechanobiology of model organisms |
| 264 | 1 | b Elsevier,c 2018 |
| 338 | a print2 rdacarrier | |
| 520 | a Mechanical stimuli play a critical role in organ development, tissue homeostasis, and disease. Understanding how mechanical signals are processed in multicellular model systems is critical for connecting cellular processes to tissue- and organism-level responses. However, progress in the field that studies these phenomena, mechanobiology, has been limited by lack of appropriate experimental techniques for applying repeatable mechanical stimuli to intact organs and model organisms. Microfluidic platforms, a subgroup of microsystems that use liquid flow for manipulation of objects, are a promising tool for studying mechanobiology of small model organisms due to their size scale and ease of customization. In this work, we describe design considerations involved in developing a microfluidic device for studying mechanobiology. Then, focusing on worms, fruit flies, and zebrafish, we review current microfluidic platforms for mechanobiology of multicellular model organisms and their tissues and highlight research opportunities in this developing field. | |
| 650 | 7 | a TEKNIK OCH TEKNOLOGIERx Annan teknikx Övrig annan teknik0 (SwePub)211992 hsv//swe |
| 650 | 7 | a ENGINEERING AND TECHNOLOGYx Other Engineering and Technologiesx Other Engineering and Technologies not elsewhere specified0 (SwePub)211992 hsv//eng |
| 653 | a C. elegans | |
| 653 | a Drosophila | |
| 653 | a Mechanobiology | |
| 653 | a Microfluidics | |
| 653 | a Multicellular model organisms | |
| 653 | a Zebrafish | |
| 700 | 1 | a Nekimken, Adam Lu Stanford University, USA4 aut |
| 700 | 1 | a Fechner, Sylviau Stanford University, USA4 aut |
| 700 | 1 | a O'Brien, Lucy Eu Stanford University, USA4 aut |
| 700 | 1 | a Pruitt, Beth Lu University of California, Santa Barbara, USA; Stanford University, USA4 aut |
| 710 | 2 | a Uppsala universitetb Mikrosystemteknik4 org |
| 773 | 0 | t Microfluidics in Cell Biology Part Ad : Elsevierg , s. 217-259q <217-259z 9780128142806 |
| 856 | 4 | u https://europepmc.org/articles/pmc6418080?pdf=render |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-358051 |
| 856 | 4 8 | u https://doi.org/10.1016/bs.mcb.2018.05.010 |
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