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Sökning: id:"swepub:oai:DiVA.org:uu-418025" > Phadiatop, Phadiato...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004768naa a2200529 4500
001oai:DiVA.org:uu-418025
003SwePub
008200831s2020 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4180252 URI
0247 a https://doi.org/10.1016/j.aller.2019.06.0132 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Pierotti, Felipe Fariau Univ Fed Sao Paulo, Sao Paulo, SP, Brazil.4 aut
2451 0a Phadiatop, Phadiatop Infant and total IgE evaluated in allergic Brazilian children and adolescents
264 1b ELSEVIER ESPANA SLU,c 2020
338 a print2 rdacarrier
520 a The clinical history is of importance in the investigation of allergic diseases but does have limitations. Many allergic conditions will be over-diagnosed if anamnesis alone is used for diagnostic criteria. Serum total immunoglobulin E (TIgE) quantification, as well as panels containing allergens prevalent in the studied population, may serve as screening tests and facilitate the diagnosis of allergic disease or its exclusion. We assessed the positivity of two versions of these tests, Phadiatop Europe (R) (PhEU) and Phadiatop Infant (R) (PhInf), as well as total IgE (TigE) values in patients with a medical diagnosis of allergic disease and non-allergic individuals. Methods: A cross-sectional study performed in eleven Brazilian pediatric allergy centers with patients divided into groups according to the primary condition and a group of assessed control subjects. They were submitted to TIgE measurement and screening tests (PhEu and PhInf). Results: TIgE mean serum levels were significantly higher among allergic patients, especially those with asthma/rhinitis or atopic dermatitis. The positivity of the screening tests, considering the total population, was 63.8% for PhEU and 72.6% for PhInf. These increased when we evaluated only the allergic subjects. The concordance index of the two tests was Kappa=0.7 and higher among those of greater age. Conclusions: In the assessed population, there were significantly higher levels among those with positive screening tests and PhInf showed better performance in the identification of sensitized individuals, regardless of age. This is the first study to evaluate Phadiatop and Phadiatop Infant in the same population. (C) 2019 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng
653 a Child
653 a Hypersensitivity
653 a Immunoglobulin E
653 a Allergens
653 a Screening tests
7001 a Aranda, Carolina Sanchezu Univ Fed Sao Paulo, Sao Paulo, SP, Brazil.4 aut
7001 a Cocco, Renata Rodriguesu Univ Fed Sao Paulo, Sao Paulo, SP, Brazil.4 aut
7001 a Sarinho, Emanuelu Univ Fed Pernambuco, Recife, PE, Brazil.4 aut
7001 a Sano, Flaviou Nipo Brasileiro Hosp, Sao Paulo, SP, Brazil.4 aut
7001 a Porto, Arnaldou Univ Passo Fundo, Passo Fundo, RS, Brazil.4 aut
7001 a Rosario, Nelsonu Univ Fed Parana, Curitiba, Parana, Brazil.4 aut
7001 a Chong Neto, Herberto Joseu Univ Fed Parana, Curitiba, Parana, Brazil.4 aut
7001 a Goudouris, Ekateriniu Univ Fed Rio de Janeiro, Rio De Janeiro, RJ, Brazil.4 aut
7001 a Moraes, Lilian Sanchesu Univ Fed Mato Grosso, Cuiaba, Mato Grosso, Brazil.4 aut
7001 a Wandalsen, Neusa Falbou Med Univ Santo Andre, Sao Paulo, SP, Brazil.4 aut
7001 a Mallozi, Marcia Carvalhou Med Univ Santo Andre, Sao Paulo, SP, Brazil.4 aut
7001 a Pastorino, Antonio Carlosu Univ Sao Paulo, Sao Paulo, SP, Brazil.4 aut
7001 a Franco, Jackeline Mottau Univ Fed Sergipe, Sao Cristovao, Sergipe, Brazil.4 aut
7001 a Chavarria, Maria Leticiau Univ Fed Goias, Goiania, Go, Brazil.4 aut
7001 a Borres, Magnus P,d 1956-u Uppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Thermo Fisher Sci, Uppsala, Sweden4 aut0 (Swepub:uu)magbo385
7001 a Sole, Dirceuu Univ Fed Sao Paulo, Sao Paulo, SP, Brazil.4 aut
7102 a Univ Fed Sao Paulo, Sao Paulo, SP, Brazil.b Univ Fed Pernambuco, Recife, PE, Brazil.4 org
7730 t Allergologia et Immunopathologiad : ELSEVIER ESPANA SLUg 48:3, s. 259-264q 48:3<259-264x 0301-0546x 1578-1267
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-418025
8564 8u https://doi.org/10.1016/j.aller.2019.06.013

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