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Surgical treatment of low-grade brain tumors associated with epilepsy

Zhang, Wei (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Chen, Junxi (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Hua, Gang (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
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Zhu, Dan (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Tan, Qinghua (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Zhang, Liming (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Wang, Genbo (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Ding, Meichao (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Hu, Xiangshu (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Li, Hua (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
Sharma, Hari Shanker (författare)
Uppsala universitet,Anestesiologi och intensivvård,Institutionen för medicinsk cellbiologi
Guo, Qiang (författare)
Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.
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Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China Anestesiologi och intensivvård (creator_code:org_t)
LONDON ENGLAND : Elsevier, 2020
2020
Engelska.
Ingår i: NOVEL THERAPEUTIC ADVANCES IN GLIOBLASTOMA. - LONDON ENGLAND : Elsevier. - 9780128211144 ; , s. 171-183
  • Bokkapitel (refereegranskat)
Abstract Ämnesord
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  • Objective: To explore the strategy of surgical treatment of low-grade brain tumors associated with epilepsy. Methods: Clinical data of 158 patients with low-grade brain tumors were collected from January 2011 to December 2017 in Guangdong Sanjiu brain hospital. All patients received Preoperative evaluation. Lesion site: 18 cases were located in multiple cerebral lobes, 10 cases were in the functional zones, 130 cases were in the non-functional zones (including 74 cases were in the medial of temporal lobe). The surgical strategy included subtotal resection, gross-total resection and enlarged resection. Postoperative effects were evaluated by Engel classification. Results: A total of 158 patients underwent surgical treatment, among these patients, only 1 patient underwent intracranial electrode implantation. Surgical methods: 34 cases of subtotal resection, 3 cases of gross-total resection, 119 cases of enlarged resection (including Anterior temporal lobectomy in 74 cases) and 2 case of Selective hippocampal amygdalectomy. The final pathology suggested that there are 74 cases of ganglionglioma, 25 cases of dysembryoplastic neuroepithelial tumors, 9 cases of pilocytic astrocytoma, 16 cases of oligodendroglioma, 10 cases of pleomorphic xanthoastrocytoma, 4 case of diffuse astrocytoma, 9 cases of unclassified astrocytoma, 11 case of oligoastrocytoma. The follow-up time was between 1 and 7 years, with an average of 3.44 +/- 1.77 years. Postoperative recovery: 147 patients had an Engel Class I outcome, 10 patients were in Engel Class II, 1 patient was in Class IV. Conclusion: The strategy of surgical treatment of low-grade brain tumors associated with epilepsy should pay more attention to the preoperative assessment of the epileptogenic zone. The tumor is not exactly the same as the epileptogenic zone, and the strategy of surgical treatment depends on the tumor feature as well as whether it was located in temporal lobe or involved in functional areas.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

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