Sökning: id:"swepub:oai:DiVA.org:uu-486990" > Clinical decision s...
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000 | 05251naa a2200457 4500 | |
001 | oai:DiVA.org:uu-486990 | |
003 | SwePub | |
008 | 221021s2022 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:liu-189346 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4869902 URI |
024 | 7 | a https://doi.org/10.1016/j.ahj.2022.02.0052 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1893462 URI |
040 | a (SwePub)uud (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Persson Lindell, Olofu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)olope88 |
245 | 1 0 | a Clinical decision support for familial hypercholesterolemia (CDS-FH) :b Rationale and design of a cluster randomized trial in primary care |
264 | 1 | b Elsevier,c 2022 |
338 | a electronic2 rdacarrier | |
520 | a Background: Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated genetic disorder with high risk of premature atherosclerotic cardiovascular disease and death. Clinical decision support (CDS) systems have the potential to aid in the identification and management of patients with FH. Prior studies using computer-based systems to screen patients for FH have shown promising results, but there has been no randomized controlled trial conducted. The aim of the current cluster randomized study is to evaluate if a CDS can increase the identification of FH.Methods: We have developed a CDS integrated in the electronic health records that will be activated in patients with elevated cholesterol levels (total cholesterol > 8 mmol/L or low-density lipoprotein-cholesterol > 5.5 mmol/L, adjusted for age, ongoing lipid lowering therapy and presence of premature coronar y arter y disease) at increased risk for FH. When activated, the CDS will urge the physician to send an automatically generated referral to the local lipid clinic for further evaluation. To evaluate the effects of the CDS, all primary care clinics will be cluster randomized 1:1 to either CDS intervention or standard care in a Swedish region with almost 500,000 inhabitants. The primary endpoint will be the number of patients diagnosed with FH at 30 months. Resource use and long-term health consequences will be estimated to assess the cost-effectiveness of the intervention.Conclusion : Despite increasing awareness of FH, the condition remains underdiagnosed and undertreated. The present study will investigate whether a CDS can increase the number of patients being diagnosed with FH. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
700 | 1 | a Karlsson, Larsu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)larka64 |
700 | 1 | a Nilsson, Staffanu Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Centrumledning PVC4 aut0 (Swepub:liu)stani72 |
700 | 1 | a Charitakis, Emmanouilu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)emmch01 |
700 | 1 | a Hagström, Emilu Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Uppsala Univ, Sweden; Uppsala Univ, Sweden4 aut0 (Swepub:uu)emhag677 |
700 | 1 | a Muhr, Thomasu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)thomu80 |
700 | 1 | a Nilsson, Lennartu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US,Cty Hosp Ryhov, Sweden4 aut0 (Swepub:liu)lenni29 |
700 | 1 | a Henriksson, Martinu Linköpings universitet,Avdelningen för samhälle och hälsa,Medicinska fakulteten4 aut0 (Swepub:liu)marhe38 |
700 | 1 | a Janzon, Magnusu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)magja75 |
710 | 2 | a Linköpings universitetb Avdelningen för diagnostik och specialistmedicin4 org |
773 | 0 | t American Heart Journald : Elsevierg 247, s. 132-148q 247<132-148x 0002-8703x 1097-6744 |
856 | 4 | u https://doi.org/10.1016/j.ahj.2022.02.005y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1705326/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://doi.org/10.1016/j.ahj.2022.02.005 |
856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1704838/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-486990 |
856 | 4 8 | u https://doi.org/10.1016/j.ahj.2022.02.005 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-189346 |
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