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Synergy of nanocarr...
Synergy of nanocarriers with CRISPR-Cas9 in an emerging technology platform for biomedical appliances : Current insights and perspectives
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- Bhattacharjee, Rahul (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Jana, Ankit (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Nandi, Aditya (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Sinha, Adrija (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Bhattacharjee, Arkadyuti (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Mitra, Sagnik (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Kar, Sulagna (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Dey, Abhijit (author)
- Presidency Univ, Dept Life Sci, 86-1 Coll St, Kolkata 700073, West Bengal, India.
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- Singh, Sushil Kumar (author)
- Assam Agr Univ, Dept Agr Biotechnol, DBT NECAB, Jorhat 785013, Assam, India.
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- Varma, Rajender S. (author)
- Palacky Univ Olomouc, Czech Adv Technol & Res Inst, Reg Ctr Adv Technol & Mat, Slechtitelu 27, Olomouc 78371, Czech Republic.
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- Panda, Pritam Kumar, PhD Student, 1991- (author)
- Uppsala universitet,Materialteori,Condensed Matter Theory Group
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- Suar, Mrutyunjay (author)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.
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- Verma, Suresh K. (author)
- Uppsala universitet,Materialteori,Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India.,Condensed Matter Theory Group
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Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Odisha, India Presidency Univ, Dept Life Sci, 86-1 Coll St, Kolkata 700073, West Bengal, India. (creator_code:org_t)
- Elsevier, 2022
- 2022
- English.
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In: Materials & design. - : Elsevier. - 0264-1275 .- 1873-4197. ; 224
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Abstract
Subject headings
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- Genetic editing technologies have emerged as a potential therapeutic tool in various biomedical fields owing to their applications against cancer, neurological diseases, diabetes, autoimmune disorder, muscu-lar dystrophy, bacterial infections (AMR), and cardiovascular diseases. CRISPR is one such valuable genetic editing tool with extensive therapeutic appliances but with a major challenge in terms of deliv-ery. Herein, we have strived to exploit a synergy of nanocarriers and CRISPR against the aforementioned diseases for their medical applications and explicated their clinical significance including the enhanced delivery via endosomal escape and environmental factors such as light, pH, and stimuli. In addition to highlighting the delivery strategies of nano-carriers for CRISPR and their characterization, we have expounded on the reliant factor of the CRISPR-Cas Complex.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
Keyword
- Nanocarriers
- CRISPR-Cas complex
- Non -viral vector
- Genome editing
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Bhattacharjee, R ...
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Jana, Ankit
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Nandi, Aditya
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Sinha, Adrija
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Bhattacharjee, A ...
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Mitra, Sagnik
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Kar, Sulagna
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Dey, Abhijit
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Singh, Sushil Ku ...
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Varma, Rajender ...
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Panda, Pritam Ku ...
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Suar, Mrutyunjay
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Verma, Suresh K.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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and Medical Biotechn ...
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Materials & desi ...
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Uppsala University