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Search: id:"swepub:oai:DiVA.org:uu-518472" > Long-Term Outcome o...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005366naa a2200541 4500
001oai:DiVA.org:uu-518472
003SwePub
008231219s2023 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:37667843-09bd-4033-be63-9683beb0ce1b
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5184722 URI
0247 a https://doi.org/10.1089/whr.2023.00732 DOI
0247 a https://lup.lub.lu.se/record/37667843-09bd-4033-be63-9683beb0ce1b2 URI
040 a (SwePub)uud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Calissendorff, Janu Karolinska Institute,Karolinska University Hospital4 aut
2451 0a Long-Term Outcome of Graves' Disease :b A Gender Perspective
264 1b Mary Ann Liebert,c 2023
338 a electronic2 rdacarrier
520 a Introduction: In gender-skewed conditions such as Graves' disease (GD), the outcome naturally becomes dominated by the majority. This may lead to gender-biased misunderstandings regarding treatment outcomes. This especially holds true when complications, such as depression, are unevenly distributed. We have, therefore, studied the long-term outcome of GD from a gender perspective.Materials and Methods: A cohort of 1186 patients with GD was included in a follow-up 6-10 years after inclusion. Choice of treatment, the feeling of recovery, long-term treatment, comorbidity, and quality of life were investigated with questionnaires. All results were studied sex-divided.Results: We included 973 women and 213 men. There was no difference between men and women in the choice of treatment. At follow-up, women scored significantly worse in the general questionnaire 36-item Short-Form Health Status (SF-36) domain bodily pain and in the thyroid-specific Thyroid-Related Patient-Reported Outcome (ThyPRO) domains depression, impaired sex life, and cosmetic complaints, all p < 0.05. Women were twice as likely (29.5%) to be treated with levothyroxine after successful treatment with antithyroid drugs (ATD) compared with men (14.9%, p < 0.05).Conclusion: After treatment for GD, women were more affected by depression, impaired sex life, cosmetic issues, and bodily pain despite successful cure of hyperthyroidism. The prevalence of hypothyroidism was also doubled in women. Whether these observed gender differences reflect a worse outcome of GD in women or a natural consequence of a higher prevalence of these symptoms and autoimmunity in the female population is difficult to disentangle. Nevertheless, several years after GD, women reveal more persistent symptoms.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng
653 a quality of life
653 a long-term follow-up
653 a Graves disease
653 a Graves disease
653 a long-term follow-up
653 a quality of life
7001 a Cramon, Per Karkovu Rigshospitalet, Copenhagen Univ Hosp, Dept Clin Physiol & Nucl Med, Copenhagen, Denmark.,Copenhagen University Hospital4 aut
7001 a Hallengren, Bengtu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-bha
7001 a Khamisi, Selwanu Uppsala University,Uppsala universitet,Endokrinologi och mineralmetabolism,Uppsala Univ Hosp, Dept Endocrinol & Diabet, Uppsala, Sweden.,Uppsala University Hospital4 aut0 (Swepub:uu)selkh262
7001 a Lantz, Mikaelu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-mla
7001 a Planck, Terezau Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-tvo
7001 a Sjölin, Gabrielu Örebro Univ Hosp, Fac Med & Hlth, Örebro, Sweden.,Örebro University Hospital4 aut
7001 a Wallin, Göranu Karolinska Institute,Örebro University Hospital4 aut
7001 a Holmberg, Matsu Karolinska Institute,Karolinska University Hospital4 aut
7102 a Karolinska Instituteb Karolinska University Hospital4 org
7730 t Women's Health Reportsd : Mary Ann Liebertg 4:1, s. 487-496q 4:1<487-496x 2688-4844
8564 u https://doi.org/10.1089/whr.2023.0073y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1821234/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u http://dx.doi.org/10.1089/whr.2023.0073x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-518472
8564 8u https://doi.org/10.1089/whr.2023.0073
8564 8u https://lup.lub.lu.se/record/37667843-09bd-4033-be63-9683beb0ce1b

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