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Pressure-controlled...
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Edmark, Lennart,1954-Uppsala universitet,Centrum för klinisk forskning, Västerås,Vastmanland Hosp Koping, Dept Anaesthes & Intens Care, Koping, Sweden.
(författare)
Pressure-controlled versus manual facemask ventilation for anaesthetic induction in adults : A randomised controlled non-inferiority trial
- Artikel/kapitelEngelska2023
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John Wiley & Sons,2023
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LIBRIS-ID:oai:DiVA.org:uu-519659
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-519659URI
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https://doi.org/10.1111/aas.14308DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Background: Pressure-controlled face mask ventilation (PC-FMV) with positive end-expiratory pressure (PEEP) after apnoea following induction of general anaesthesia prolongs safe apnoea time and reduces atelectasis formation. However, depending on the set inspiratory pressure, a delayed confirmation of a patent airway might occur. We hypothesised that by lowering the peak inspiratory pressure (PIP) when using PC-FMV with PEEP, confirmation of a patent airway would not be delayed as studied by the first return of CO2, compared with manual face mask ventilation (Manual FMV).Methods: This was a single-centre, randomised controlled non-inferiority trial. Seventy adult patients scheduled for elective day-case surgery under general anaesthesia with body mass index between 18.5 and 29.9 kg m(-2), American Society of Anesthesiologists (ASA) classes I-III, and without anticipated difficult FMV, were included. Before the start of pre-oxygenation and induction of general anaesthesia, participants were randomly allocated to receive ventilation with either PC-FMV with PEEP, at a PIP of 11 and a PEEP of 6 cmH(2)O or Manual FMV, with the adjustable pressure-limiting valve set at 11 cmH(2)O. The primary outcome variable was the number of ventilatory attempts needed until confirmation of a patent airway, defined as the return of at least 1.3 kPa CO2.Results: The return of >= 1.3 kPa CO2 on the capnography curve was observed after mean +/- SD, 3.6 +/- 4.2 and 2.5 +/- 1.9 ventilatory attempts/breaths with PC-FMV with PEEP and Manual FMV, respectively. The difference in means (1.1 ventilatory attempts/breaths) had a 99% CI of similar to 1.0 to 3.1, within the accepted upper margin of four breaths for non-inferiority.Conclusion: Following induction of general anaesthesia, PC-FMV with PEEP was used without delaying a patent airway as confirmed with capnography, if moderate pressures were used.
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Englund, Emma-KarinVastmanland Hosp Koping, Dept Anaesthes & Intens Care, Koping, Sweden.
(författare)
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Jonsson, Alexandra SchottleVastmanland Hosp Koping, Dept Anaesthes & Intens Care, Koping, Sweden.
(författare)
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Zilic, Almira TeskeredzicVastmanland Hosp Koping, Dept Anaesthes & Intens Care, Koping, Sweden.
(författare)
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Cajander, PerÖrebro Univ, Örebro Univ Hosp, Sch Med Sci, Dept Anaesthes & Intens Care, Örebro, Sweden.
(författare)
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Östberg, Erland,1971-Uppsala universitet,Centrum för klinisk forskning, Västerås,Vastmanland Hosp Koping, Dept Anaesthes & Intens Care, Koping, Sweden.;Reg Vastmanland Uppsala Univ, Vastmanland Hosp Västerås, Ctr Clin Res, Västerås, Sweden.(Swepub:uu)erlos960
(författare)
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Uppsala universitetCentrum för klinisk forskning, Västerås
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Acta Anaesthesiologica Scandinavica: John Wiley & Sons67:10, s. 1356-13620001-51721399-6576
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