id:"swepub:oai:DiVA.org:uu-73100"
Sökning: id:"swepub:oai:DiVA.org:uu-73100" > An ordinary mixed m...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03929naa a2200565 4500 | |
| 001 | oai:DiVA.org:uu-73100 | |
| 003 | SwePub | |
| 008 | 080611s2001 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-731002 URI |
| 024 | 7 | a https://doi.org/10.1046/j.1365-201X.2001.00845.x2 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Sarabi, Mahziaru Uppsala universitet,Institutionen för medicinska vetenskaper,Akut- och internmedicin4 aut |
| 245 | 1 0 | a An ordinary mixed meal transiently impairs endothelium-dependent vasodilation in healthy subjects |
| 264 | 1 | c 2001 |
| 338 | a print2 rdacarrier | |
| 520 | a This study was designed to evaluate the effects of an ordinary mixed meal on endothelium-dependent vasodilation. Ten young healthy volunteers were given a mixed meal (minced meat sauce with rice, 900 kcal, 34% of the energy content was fat). In the fasting state, at 60 and 120 min after the start of the meal, endothelium-dependent vasodilation and endothelium-independent vasodilation were evaluated by local infusion of metacholine (4 microg min (-1)) and sodium nitroprusside (10 microg min (-1)) in the brachial artery. Blood flow in the forearm was measured using venous occlusion plethysmography. Endothelium-dependent vasodilation decreased from 15.4 +/- 3.3 (mean +/- SD) at fasting to 13.7 +/- 3.5 mL min (-1) (100 mL tissue)-1 (P < 0.01) 60 min after feeding, but had returned to the fasting level at 120 min. At 60 min, but not in the fasting state, the serum level of free fatty acids was inversely related to endothelium-dependent vasodilation (r=-0.74, P < 0.05), although no significant net changes in FFA levels were seen. Endothelium-independent vasodilation was not affected by the mixed meal. No similar attenuations in endothelium-dependent vasodilation were seen during control meals. In conclusion, an ordinary mixed meal transiently attenuated endothelium-dependent vasodilation. Free fatty acids may be involved in this effect on endothelial function. | |
| 653 | a Adult | |
| 653 | a Blood Flow Velocity/drug effects | |
| 653 | a Chemistry; Clinical | |
| 653 | a Choline/pharmacology | |
| 653 | a Eating/*physiology | |
| 653 | a Endothelium; Vascular/drug effects/physiology | |
| 653 | a Fasting/physiology/psychology | |
| 653 | a Fatty Acids; Nonesterified/blood | |
| 653 | a Female | |
| 653 | a Food | |
| 653 | a Food Deprivation/physiology | |
| 653 | a Forearm/blood supply | |
| 653 | a Humans | |
| 653 | a Male | |
| 653 | a Nitroprusside/pharmacology | |
| 653 | a Plethysmography | |
| 653 | a Triglycerides/blood | |
| 653 | a Vasodilation/drug effects/*physiology | |
| 653 | a MEDICINE | |
| 653 | a MEDICIN | |
| 700 | 1 | a Fugmann, Andreasu Uppsala universitet,Institutionen för medicinska vetenskaper,Akut- och internmedicin4 aut |
| 700 | 1 | a Karlström, Britau Uppsala universitet,Institutionen för folkhälso- och vårdvetenskap,Geriatrics4 aut0 (Swepub:uu)britkarl |
| 700 | 1 | a Berne, Christianu Uppsala universitet,Institutionen för medicinska vetenskaper4 aut0 (Swepub:uu)chber255 |
| 700 | 1 | a Lithell, Hansu Uppsala universitet,Institutionen för folkhälso- och vårdvetenskap,Geriatrics4 aut |
| 700 | 1 | a Lind, Larsu Uppsala universitet,Institutionen för medicinska vetenskaper,Akut- och internmedicin4 aut0 (Swepub:uu)larslind |
| 710 | 2 | a Uppsala universitetb Institutionen för medicinska vetenskaper4 org |
| 773 | 0 | t Acta Physiologica Scandinavicag 172:2, s. 107-113q 172:2<107-113x 0001-6772x 1365-201X |
| 856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=11442450&dopt=Citation |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-73100 |
| 856 | 4 8 | u https://doi.org/10.1046/j.1365-201X.2001.00845.x |
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