Search: id:"swepub:oai:DiVA.org:uu-79672" >
Acute effects of a ...
Acute effects of a fungal volatile compound
-
- Wålinder, Robert (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Eva Vingård
-
- Ernstgård, Lena (author)
- Karolinska Institutet
-
- Johanson, Gunnar (author)
- Karolinska Institutet
-
show more...
-
- Norbäck, Dan (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Institutionen för neurovetenskap,Eva Vingård
-
- Venge, Per (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper
-
- Wieslander, Gunilla (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Eva Vingård
-
show less...
-
(creator_code:org_t)
- Environmental Health Perspectives, 2005
- 2005
- English.
-
In: Journal of Environmental Health Perspectives. - : Environmental Health Perspectives. - 0091-6765 .- 1552-9924. ; 113:12, s. 1775-1778
- Related links:
-
http://www.ncbi.nlm....
-
show more...
-
https://www.ncbi.nlm...
-
https://urn.kb.se/re...
-
http://kipublication...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- OBJECTIVE: 3-Methylfuran (3-MF) is a common fungal volatile product with active biologic properties, and previous studies have indicated a contribution to airway disease. The aim of the present study was to assess the acute health effects of this compound in humans. DESIGN: Acute effects were assessed via chamber exposure to (1 mg/m3) 3-MF. PARTICIPANTS AND MEASUREMENTS: Twenty-nine volunteers provided symptom reports, ocular electromyograms, measurement of eye tear film break-up time,vital staining of the eye, nasal lavage, acoustic rhinometry, transfer tests, and dynamic spirometry. RESULTS: No subjective ratings were significantly increased during exposure. Blinking frequency and the lavage biomarkers myeloperoxidase and lysozyme were significantly increased, and forced vital capacity was significantly decreased during exposure to 3-MF compared with air control. CONCLUSIONS AND RELEVANCE TO CLINICAL PRACTICE: Acute effects in the eyes, nose, and airways were detected and might be the result of the biologically active properties of 3-MF. Thus, 3-MF may contribute to building-related illness.
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database