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Retinoic acid receptor retinoid X receptor heterodimers can be activated through both subunits providing a basis for synergistic transactivation and cellular differentiation
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- Botling, J (author)
- Uppsala universitet
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- Castro, DS (author)
- Uppsala universitet
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- Oberg, F (author)
- Uppsala universitet
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- AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1997
- 1997
- English.
- In: JOURNAL OF BIOLOGICAL CHEMISTRY. - : AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. - 0021-9258. ; 272:14, s. 9443-9449
- Journal article (other academic/artistic)
Abstract
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- The receptor for 9-cis-retinoic acid, retinoid X receptor (RXR), forms heterodimers with several nuclear receptors, including the receptor for all-trans-retinoic acid, RAR. Previous studies have shown that retinoic acid receptor can be activated in RAR/RX
Keyword
- THYROID-HORMONE RECEPTOR; LIGAND-BINDING DOMAIN; NUCLEAR RECEPTOR; CO-REPRESSOR; TRANSCRIPTIONAL ACTIVATION; RESPONSE PATHWAYS; CRYSTAL-STRUCTURE; LINE U-937; BETA-GENE; PROLIFERATION
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- art (subject category)
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