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Brief questionnaires for patient-reported outcomes in asthma : validation and usefulness in a primary care setting

Ehrs, Per-Olof (författare)
Nokela, Mika (författare)
Ställberg, Björn (författare)
Uppsala universitet,Allmänmedicin och klinisk epidemiologi,Centrum för klinisk forskning i D län (CKFD)
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Hjemdahl, Paul (författare)
Karolinska Institutet
Wikström Jonsson, Eva (författare)
Karolinska Institutet
Nokela, A (författare)
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 (creator_code:org_t)
Elsevier BV, 2006
2006
Engelska.
Ingår i: Chest. - : Elsevier BV. - 0012-3692 .- 1931-3543. ; 129:4, s. 925-932
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • OBJECTIVES AND DESIGN: Health-related quality of life (QoL) instruments are generally used for studies of asthma in specialized settings. For primary care use, there is a need for brief and simple questionnaires for structured patient-reported outcomes. We validated the Mini-Asthma Quality of Life Questionnaire (Mini-AQLQ), using the Asthma Quality of Life Questionnaire with standardized activities (AQLQ[S]) as the "gold standard." The Asthma Control Questionnaire (ACQ) was validated against the symptoms domain of the AQLQ(S). Patients were characterized by the Short Form-36 Health Survey (SF-36). SUBJECTS: One hundred eight patients (68 women) with asthma diagnosed by their physicians from 24 primary care centers completed two visits (2 to 3 months apart). Their mean SF-36 scores were lower than the national norm for all domains. RESULTS: The Mini-AQLQ and ACQ correlated well with the AQLQ(S). Reliability, determined in 57 patients with stable AQLQ(S) scores, was good. Both brief questionnaires detected improvement or deterioration of patients at the group level. Global ratings of disease severity by patients or clinicians correlated poorly with disease-specific QoL scores. CONCLUSIONS: The Mini-AQLQ and ACQ instruments are sufficiently simple and robust to be suitable for research and quality of care monitoring in primary care at the group level. They may, after further validation, even be useful in the management of individual patients.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)

Nyckelord

Adolescent
Adult
Aged
Aged; 80 and over
Asthma/psychology/*therapy
Female
Health Status
Humans
Male
Middle Aged
Primary Health Care
Prospective Studies
Quality of Life
Questionnaires
Reproducibility of Results
Research Support; Non-U.S. Gov't
Treatment Outcome
Lung diseases
Lungsjukdomar

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