id:"swepub:oai:DiVA.org:uu-90770"
Sökning: id:"swepub:oai:DiVA.org:uu-90770" > Serum VEGF and bFGF...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03689naa a2200625 4500 | |
| 001 | oai:DiVA.org:uu-90770 | |
| 003 | SwePub | |
| 008 | 030912s2003 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:1945629 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-907702 URI |
| 024 | 7 | a https://doi.org/10.1016/j.lungcan.2003.07.0072 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19456292 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Brattström, Danielu Uppsala universitet,Enheten för onkologi,G Wagenius4 aut |
| 245 | 1 0 | a Serum VEGF and bFGF adds prognostic information in patients with normal platelet counts when sampled before, during and after treatment for locally advanced non-small cell lung cancer |
| 264 | 1 | b Elsevier BV,c 2003 |
| 338 | a print2 rdacarrier | |
| 520 | a Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) have both been implicated to have roles in tumour angiogenesis. In the present retrospective study, serum VEGF and bFGF from patients with locally advanced non-small cell lung cancer (NSCLC) were analysed before, during and after treatment. Seventy-three patients and a total of 460 serum samples were analysed for VEGF and 443 serum samples were analysed for bFGF. Pre-treatment bFGF levels in patients with normal platelet counts, were correlated to poorer survival, P-value = 0.047. During chemotherapy, each rise of one unit bFGF corresponded to a hazard ratio of 4.06 (P=0.022). In patients with normal platelet counts, VEGF levels after radiotherapy significantly correlated to good prognosis (P=0.023), during radiotherapy VEGF levels indicated the same correlation (P=0.085). We conclude that serum VEGF and especially bFGF are of clinical interest as prognostic factors, especially in patients presenting with normal platelet counts. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 653 | a Adult | |
| 653 | a Aged | |
| 653 | a Aged; 80 and over | |
| 653 | a Analysis of Variance | |
| 653 | a Carcinoma; Non-Small-Cell Lung/*blood/pathology/therapy | |
| 653 | a Female | |
| 653 | a Fibroblast Growth Factor 2/*blood | |
| 653 | a Humans | |
| 653 | a Lung Neoplasms/*blood/pathology/therapy | |
| 653 | a Male | |
| 653 | a Middle Aged | |
| 653 | a Neovascularization; Pathologic/blood | |
| 653 | a Platelet Count | |
| 653 | a Predictive Value of Tests | |
| 653 | a Proportional Hazards Models | |
| 653 | a Research Support; Non-U.S. Gov't | |
| 653 | a Retrospective Studies | |
| 653 | a Survival Analysis | |
| 653 | a Vascular Endothelial Growth Factor A/*blood | |
| 653 | a Oncology | |
| 653 | a Onkologi | |
| 700 | 1 | a Bergqvist, Michaelu Uppsala universitet,Enheten för onkologi4 aut |
| 700 | 1 | a Hesselius, Patrik4 aut |
| 700 | 1 | a Larsson, Andersu Uppsala universitet,Klinisk kemi4 aut |
| 700 | 1 | a Wagenius, Gunnaru Uppsala universitet,Enheten för onkologi4 aut |
| 700 | 1 | a Brodin, Olau Karolinska Institutet4 aut |
| 710 | 2 | a Uppsala universitetb Enheten för onkologi4 org |
| 773 | 0 | t Lung Cancerd : Elsevier BVg 43:1, s. 55-62q 43:1<55-62x 0169-5002x 1872-8332 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-90770 |
| 856 | 4 8 | u https://doi.org/10.1016/j.lungcan.2003.07.007 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1945629 |
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