Sökning: id:"swepub:oai:DiVA.org:uu-97931" > The Role of Circula...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03269naa a2200421 4500 | |
001 | oai:DiVA.org:uu-97931 | |
003 | SwePub | |
008 | 081222s2007 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-979312 URI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bolander, Åsau Uppsala universitet,Enheten för onkologi4 aut |
245 | 1 0 | a The Role of Circulating Angiogenic Factors in Patients Operated on for Localized Malignant Melanoma |
264 | 1 | c 2007 |
338 | a print2 rdacarrier | |
520 | a Malignant melanoma is a disease capable of rapid progression and rapidly developing metastases. Angiogenesis is a key event signalling tumour progression and elevated levels of angiogenic markers may indicate metastatic disease. No previously published work has, so far, examined plasma vascular endothelial growth factor (VEGF) and its receptor, VEGFR-1, in melanoma. This study investigated circulating levels of the angiogenic factors, VEGF-A and -D, their receptors 1-3 and hepatocyte growth factor (HGF)/scatter factor, in patients shortly after primary surgery for localized malignant melanoma. Elevated circulating levels of VEGF and its receptors, and of HGF, were found postoperatively, possibly derived from the reactive stroma adjacent to the tumours. Using univariate analysis, a correlation between levels of VEGFR-1 and relapse was found, but a correlation between the investigated angiogenic factors and survival could not be established. The results of the present study indicate that production of these angiogenic factors may be due to sources other than malignant melanoma cells. | |
653 | a Malignant melanoma | |
653 | a angiogenesis | |
653 | a survival | |
653 | a relapse | |
653 | a vascular endothelial growth factor | |
653 | a hepatocyte growth factor | |
653 | a hepatocyte scatter factor | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Wagenius, Gunnaru Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,Lunggruppen4 aut0 (Swepub:uu)gunnwage |
700 | 1 | a Larsson, Andersu Uppsala universitet,Klinisk kemi,Biologisk struktur och funktion4 aut0 (Swepub:uu)andlarss |
700 | 1 | a Brattström, Danielu Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,Lymfomgruppen4 aut0 (Swepub:uu)danibrat |
700 | 1 | a Ullenhag, Gustavu Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi4 aut0 (Swepub:uu)gustulle |
700 | 1 | a Hesselius, Patriku Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi4 aut0 (Swepub:uu)patrhess |
700 | 1 | a Ekman, Simonu Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,Lunggruppen4 aut |
700 | 1 | a Bergqvist, Michaelu Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,Lunggruppen4 aut0 (Swepub:uu)michberg |
710 | 2 | a Uppsala universitetb Enheten för onkologi4 org |
773 | 0 | t Anticancer Researchg 27:5A, s. 3211-3217q 27:5A<3211-3217x 0250-7005x 1791-7530 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-97931 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.