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Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative.
- Vanderstichele, Hugo (author)
- Bibl, Mirko (author)
- Engelborghs, Sebastiaan (author)
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- Le Bastard, Nathalie (author)
- Lewczuk, Piotr (author)
- Molinuevo, Jose Luis (author)
- Parnetti, Lucilla (author)
- Perret-Liaudet, Armand (author)
- Shaw, Leslie M (author)
- Teunissen, Charlotte (author)
- Wouters, Dirk (author)
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- (creator_code:org_t)
- 2011-11-03
- 2012
- English.
- In: Alzheimer's & dementia : the journal of the Alzheimer's Association. - : Wiley. - 1552-5279. ; 8:1, s. 65-73
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Numerous studies show that the cerebrospinal fluid biomarkers total tau (T-tau), tau phosphorylated at threonine 181 (P-tau(181P)), and amyloid-β (1-42) (Aβ(1-42)) have high diagnostic accuracy for Alzheimer's disease. Variability in concentrations for Aβ(1-42), T-tau, and P-tau(181P) drives the need for standardization.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- Alzheimer Disease
- cerebrospinal fluid
- diagnosis
- Amyloid beta-Peptides
- cerebrospinal fluid
- Biological Markers
- cerebrospinal fluid
- Consensus
- Guidelines as Topic
- standards
- Humans
- Peptide Fragments
- cerebrospinal fluid
- Quality Control
- Reproducibility of Results
- tau Proteins
- cerebrospinal fluid
Publication and Content Type
- ref (subject category)
- art (subject category)
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