Norovirus GII.4 Virus-like Particles Recognize Galactosylceramides in Domains of Planar Supported Lipid Bilayers.

Bally, Marta, 1981 (author): Chalmers tekniska högskola,Chalmers University of Technology,Chalmers, Sweden

Rydell, Gustaf E (author): Centre national de la recherche scientifique (CNRS),Institute Curie, France

Zahn, Raphael (author): Eidgenössische Technische Hochschule Zürich (ETH),Swiss Federal Institute of Technology in Zürich (ETH),University of Zurich, Switzerland Swiss Federal Institute Technology, Switzerland

Nasir, Waqas (author): Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine,University of Gothenburg,University of Gothenburg, Sweden

Eggeling, Christian (author): University Of Oxford,Max Planck Gesellschaft zur Förderung der Wissenschaften e.V. (MPG),Max Planck Society for the Advancement of Science (MPG),Max Planck Institute Biophys Chemistry, Germany

Breimer, Michael, 1951 (author): Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,University of Gothenburg,University of Gothenburg, Sweden

Svensson, Lennart (author): Linköpings universitet,Molekylär virologi,Hälsouniversitetet

Höök, Fredrik, 1966 (author): Chalmers tekniska högskola,Chalmers University of Technology,Chalmers, Sweden

Larson, Göran, 1953 (author): Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine,University of Gothenburg,University of Gothenburg, Sweden

(creator_code:org_t)

2012-10-24
2012
English.
In: Angewandte Chemie International Edition. - : Wiley. - 1433-7851 .- 1521-3773. ; 51:48, s. 12020-4

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Abstract Subject headings

A sticky situation: Domain-dependent recognition of the glycosphingolipid galactosylceramide by norovirus-like particles (see picture; red/yellow) is shown using supported lipid bilayers (purple) as model membranes. Optimal ligand presentation is found to promote strong binding to GalCer. This presentation can be found at the edges of the glycosphingolipid-enriched domains (green) and binding is repressed in the absence of these domains.

MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Andra medicinska och farmaceutiska grundvetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Other Basic Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
NATURVETENSKAP -- Biologi -- Biofysik (hsv//swe)
NATURAL SCIENCES -- Biological Sciences -- Biophysics (hsv//eng)

galactosylceramide; glycolipids; noroviruses; supported lipid bilayer; viruses
MEDICINE

By the author/editor: Bally, Marta, 19 ...; Rydell, Gustaf E; Zahn, Raphael; Nasir, Waqas; Eggeling, Christ ...; Breimer, Michael ...; show more...; Svensson, Lennar ...; Höök, Fredrik, 1 ...; Larson, Göran, 1 ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Microbiology in ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Other Basic Medi ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Cell and Molecul ...

NATURAL SCIENCES: NATURAL SCIENCES; and Biological Scien ...; and Biophysics

By the university: University of Gothenburg; Chalmers University of Technology; Linköping University

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