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Mast cell tryptase ...
Mast cell tryptase stimulates production of decorin by human testicular peritubular cells: possible role of decorin in male infertility by interfering with growth factor signaling.
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Adam, M (author)
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Schwarzer, J U (author)
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Köhn, F M (author)
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Strauss, L (author)
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- Poutanen, Matti (author)
- Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research
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Mayerhofer, A (author)
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(creator_code:org_t)
- 2011-07-25
- 2011
- English.
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In: Human reproduction (Oxford, England). - : Oxford University Press (OUP). - 1460-2350 .- 0268-1161. ; 26:10, s. 2613-25
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https://academic.oup...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Myofibroblastic, peritubular cells in the walls of seminiferous tubules produce low levels of the extracellular matrix (ECM) protein decorin (DCN), which has the ability to interfere with growth factor (GF) signaling. In men with impaired spermatogenesis, fibrotic remodeling of these walls and accumulation of tryptase-positive mast cells (MCs) occur.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Biopsy
- methods
- Calcium
- metabolism
- Cell Proliferation
- Cell Survival
- Decorin
- biosynthesis
- Fibrosis
- pathology
- Humans
- Infertility
- Male
- metabolism
- Intercellular Signaling Peptides and Proteins
- metabolism
- Male
- Mast Cells
- cytology
- Phosphorylation
- Signal Transduction
- Spermatogenesis
- Testis
- metabolism
- pathology
- Tryptases
- biosynthesis
- metabolism
- physiology
Publication and Content Type
- ref (subject category)
- art (subject category)
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