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An in vitro and in vivo Comparison of the Effect of Stevia rebaudiana Extracts on Different Caries-Related Variables: A Randomized Controlled Trial Pilot Study
- Brambilla, E. (author)
- Cagetti, M. G. (author)
- Ionescu, A. (author)
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- Campus, G. (author)
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- (creator_code:org_t)
- 2013-11-06
- 2014
- English.
- In: Caries Research. - : S. Karger AG. - 0008-6568 .- 1421-976X. ; 48:1, s. 19-23
- Journal article (peer-reviewed)
Abstract
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- The effect of Stevia extracts on in vitro Streptococcus mutans biofilm formation and in vivo plaque pH was evaluated in this paper. Three 10% solutions containing stevioside, rebaudioside A or sucrose were prepared. MIT assay was used to evaluate microbiological counts in vitro. Twenty volunteers rinsed for 1 min with each solutions, and plaque pH was measured at 7 time points after each rinse. Higher in vitro S. mutans biofilm formation was observed in sucrose solution (p < 0.01). After 5, 10, 15 and 30 min, the sucrose in vivo rinse produced a statistically significantly lower pH value compared to the Stevia extracts (F = 99.45, p < 0.01). Stevia extracts can be considered nonacidogenic. (C) 20135. Karger AG, Basel
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Keyword
- Caries
- Plaque pH
- Rebaudioside A
- Stevioside
- INTENSE NATURAL SWEETENERS
- DENTAL-CARIES
- PLAQUE-PH
- STEVIOSIDE
- SWEETNESS
- SUCROSE
- 2-YEAR
- RISK
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- ref (subject category)
- art (subject category)
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- Cagetti, M. G.
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- University of Gothenburg
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