Effects of epinephrine, norepinephrine, magnesium sulfate, and milrinone on survival and the occurrence of arrhythmias in amitriptyline poisoning in the rat.

• Cardiac depression is the main adverse effect of severe tricyclic antidepressant poisoning. The aim of this study was to compare the effects of several inotropic drugs on survival and the occurrence of arrhythmias in the treatment of amitriptyline poisoning.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)

Keyword

Amitriptyline

poisoning

Analysis of Variance

Animals

Arrhythmias

Cardiac

chemically induced

mortality

prevention & control

Cardiotonic Agents

therapeutic use

Chi-Square Distribution

Drug Evaluation

Preclinical

Drug Therapy

Combination

Epinephrine

therapeutic use

Magnesium Sulfate

therapeutic use

Male

Milrinone

Norepinephrine

therapeutic use

Poisoning

complications

drug therapy

mortality

Pyridones

therapeutic use

Rats

Rats

Wistar

Survival Analysis

Time Factors

Publication and Content Type

ref (subject category)

art (subject category)