Multivariate evaluation of doxorubicin surface-enhanced Raman spectra.

Eliasson, Charlotte, 1973 (author): Chalmers tekniska högskola,Chalmers University of Technology

Lorén, Anders, 1974 (author): Chalmers tekniska högskola,Chalmers University of Technology

Murty, K V (author)

Josefson, M (author)

Käll, Mikael, 1963 (author): Gothenburg University,Göteborgs universitet,Institutionen för fysik (GU),Department of Physics (GU),University of Gothenburg

Abrahamsson, Jonas, 1954 (author): Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics,University of Gothenburg

Abrahamsson, Katarina, 1957 (author): Gothenburg University,Göteborgs universitet,Institutionen för kemi,Department of Chemistry,University of Gothenburg

(creator_code:org_t)

2001
2001
English.
In: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. - 1386-1425. ; 57:9, s. 1907-15

Related links:: https://gup.ub.gu.se...; show more...; https://research.cha...; show less...

Abstract Subject headings

Multivariate evaluation of surface-enhanced Raman spectra of doxorubicin in plasma was performed. In a principal component analysis (PCA) all spectral features were modelled into three principal components. The major variation of the data was shown to be the variation of doxorubicin Raman signal together with the doxorubicin fluorescence, whereas the variation due to plasma was of minor importance. It was also shown that the surface-enhanced Raman scattering (SERS) measurements were independent on such factors as measurement occasion and silver colloids. The presented results show that with some improvements, quantification of doxorubicin directly in plasma could be possible.

MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Andra medicinska och farmaceutiska grundvetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Other Basic Medicine (hsv//eng)

By the author/editor: Eliasson, Charlo ...; Lorén, Anders, 1 ...; Murty, K V; Josefson, M; Käll, Mikael, 19 ...; Abrahamsson, Jon ...; show more...; Abrahamsson, Kat ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Other Basic Medi ...

By the university: University of Gothenburg; Chalmers University of Technology

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