id:"swepub:oai:gup.ub.gu.se/208766"
Search: id:"swepub:oai:gup.ub.gu.se/208766" > Relation of Serum U...
- 1 of 1
- Previous record
- Next record
- To hitlist
Relation of Serum Uric Acid Levels and Outcomes Among Patients Hospitalized for Worsening Heart Failure With Reduced Ejection Fraction (from the Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan Trial)
- Vaduganathan, M. (author)
- Greene, S. J. (author)
- Ambrosy, A. P. (author)
- show more...
- Mentz, R. J. (author)
- Subacius, H. P. (author)
- Chioncel, O. (author)
- Maggioni, A. P. (author)
- Zannad, F. (author)
- Konstam, M. A. (author)
- Senni, M. (author)
- Givertz, M. M. (author)
- Butler, J. (author)
- Gheorghiade, M. (author)
- show less...
- (creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
- In: American Journal of Cardiology. - : Elsevier BV. - 0002-9149. ; 114:11, s. 1713-21
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- We investigated the clinical profiles associated with serum uric acid (sUA) levels in a large cohort of patients hospitalized for worsening chronic heart failure with ejection fraction (EF) /=30 ml/min/1.73 m(2), sUA was strongly associated with increased all-cause mortality (hazard ratio 1.44, 95% confidence interval 1.22 to 1.69, p <0.001) and the composite end point (hazard ratio 1.44, 95% confidence interval 1.26 to 1.64, p <0.001). However, in patients with estimated glomerular filtration rate <30 ml/min/1.73 m(2), sUA was not related with either end point (both p >0.4). Adjusted interaction analyses for gender, race, and admission allopurinol use were not significant. In conclusion, sUA is commonly elevated in patients hospitalized for worsening chronic heart failure and reduced EF, especially in men and blacks. The prognostic use of sUA differs by baseline renal function, suggesting different biologic and pathophysiologic significance of sUA among those with and without significant renal dysfunction.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- American Journal of Cardiology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Vaduganathan, M.
- Greene, S. J.
- Ambrosy, A. P.
- Mentz, R. J.
- Subacius, H. P.
- Chioncel, O.
- show more...
- Maggioni, A. P.
- Swedberg, Karl, ...
- Zannad, F.
- Konstam, M. A.
- Senni, M.
- Givertz, M. M.
- Butler, J.
- Gheorghiade, M.
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- Articles in the publication
- American Journal ...
- By the university
- University of Gothenburg
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
