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Survivin but not Fms-like tyrosine kinase 3 ligand is up-regulated before the onset of rheumatoid arthritis: a pilot study.

Bokarewa, Maria, 1963 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
Brink, Mikael (author)
Umeå universitet,Reumatologi
Erlandsson, Malin, 1972 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
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Rantapää-Dahlqvist, Solbritt (author)
Umeå universitet,Reumatologi
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 (creator_code:org_t)
Springer Science and Business Media LLC, 2014
2014
English.
In: Arthritis research & therapy. - : Springer Science and Business Media LLC. - 1478-6362 .- 1478-6354. ; 16:1
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Antibodies against citrullinated peptides (anti-CCP) and increased levels of cytokines precede the development of rheumatoid arthritis (RA) by several years. Recently, the proteins survivin and Fms-like tyrosine kinase 3 ligand (Flt3L) have been identified as biomarkers of RA associated with joint destruction. Our objective was to investigate the potential of survivin and Flt3L as predictors of RA in samples from patients prior to onset of symptoms.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

Arthritis
Rheumatoid
blood
immunology
Biological Markers
blood
Case-Control Studies
Enzyme-Linked Immunosorbent Assay
Female
Humans
Inhibitor of Apoptosis Proteins
blood
immunology
Male
Membrane Proteins
blood
immunology
Middle Aged
Odds Ratio
Pilot Projects
Up-Regulation

Publication and Content Type

ref (subject category)
art (subject category)

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