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Sökning: id:"swepub:oai:gup.ub.gu.se/261582" > Temporal patterns o...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004621naa a2200385 4500
001oai:gup.ub.gu.se/261582
003SwePub
008240528s2018 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/2615822 URI
024a https://doi.org/10.1111/coa.128962 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Thor, M4 aut
2451 0a Temporal patterns of patient-reported trismus and associated mouth-opening distances in radiotherapy for head and neck cancer: A prospective cohort study.
264 c 2017-05-29
264 1b Wiley,c 2018
520 a To identify temporal patterns of patient-reported trismus during the first year post-radiotherapy, and to study their associations with maximal interincisal opening distances (MIOs).Single institution case series.University hospital ENT clinic.One hundred and ninety-six subjects who received radiotherapy (RT) for head and neck cancer (HNC) with or without chemotherapy in 2007-2012 to a total dose of 64.6/68Gy in 38/34 fractions, respectively. All subjects were prospectively assessed for mouth-opening ability (Gothenburg Trismus Questionnaire (GTQ), European Organization for Research and Treatment of Cancer quality of life Questionnaire (EORTC QLQ-H&N35), and MIO) pre-RT and at 3, 6 and 12months after RT.Correlations between temporally robust GTQ symptoms and MIO as given by Pearson's correlation coefficients (Pr ); temporally robust GTQ-symptom domains as given by factor analysis; rates of trismus with respect to baseline by risk ratios (RRs).Four temporally robust domains were identified: Eating (3-7 symptoms), Jaw (3-7), Pain (2-5) and Quality of Life (QoL, 2-5), and included 2-3 persistent symptoms across all post-RT assessments. The median RR for a moderate/severe (>2/>3) cut-off was the highest for Jaw (3.7/3.6) and QoL (3.2/2.9). The median Pr between temporally robust symptoms and MIO post-radiotherapy was 0.25-0.35/0.34-0.43/0.24-0.31/0.34-0.50 for Eating/Jaw/Pain/QoL, respectively.Mouth-opening distances in patients with HNC post-RT can be understood in terms of associated patient-reported outcomes on trismus-related difficulties. Our data suggest that a reduction in MIO can be expected as patients communicate their mouth-opening status to interfere with private/social life, a clinical warning signal for emerging or worsening trismus as patients are being followed after RT.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
700a Olsson, Caroline,d 1970u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiofysik,Institute of Clinical Sciences, Department of Radiation Physics4 aut0 (Swepub:gu)xolcar
700a Oh, J H4 aut
700a Hedström, Johannau Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut0 (Swepub:gu)xhedsj
700a Pauli, Ninau Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut0 (Swepub:gu)xpauni
700a Johansson, Mariau Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut
700a Deasy, J O4 aut
700a Finizia, Caterina,d 1961u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology4 aut0 (Swepub:gu)xfinca
710a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för radiofysik4 org
773t Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgeryd : Wileyg 43:1, s. 22-30q 43:1<22-30x 1749-4486
773t Clinical Otolaryngologyd : Wileyg 43:1, s. 22-30q 43:1<22-30x 1749-4478
856u https://europepmc.org/articles/pmc6651728?pdf=render
8564 8u https://gup.ub.gu.se/publication/261582
8564 8u https://doi.org/10.1111/coa.12896

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