The relationship between affective symptoms and hypertension-role of the labelling effect: the 1946 British birth cohort.

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The relationship between affective symptoms and hypertension-role of the labelling effect: the 1946 British birth cohort.

Tikhonoff, Valérie (author)

Hardy, Rebecca (author)

Deanfield, John (author)

Friberg, Peter, 1956 (author): Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine

Muniz, Graciela (author)

Kuh, Diana (author)

Pariante, Carmine M (author)

Hotopf, Matthew (author)

Richards, Marcus (author)

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(creator_code:org_t)

2016-01-12
2016
English.
In: Open heart. - : BMJ. - 2053-3624. ; 3:1

Related links:: https://openheart.bm...; show more...; https://gup.ub.gu.se...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

To investigate the association between repeated measures of affective symptoms collected over 2 decades and hypertension (clinically ascertained or self-report); to test whether, among people with hypertension, affective symptoms are associated with awareness of hypertension, and to evaluate the longitudinal effects of the label of hypertension on affective symptoms.Multivariable logistic regression, accounting for confounders and mediators, were used to test the aforementioned associations in 1683 participants from a national British cohort.Weak evidence of a cumulative impact of affective symptoms across adulthood on self-reported hypertension at age 60-64years was observed (OR 1.40 (95% CI 1.10 to 1.78) and 1.19 (0.79 to 1.80) for symptoms at 1-2 time points and at 3-4 time points vs no symptoms, respectively). Study members with affective symptoms in recent times were more likely to have self-reported hypertension at age 60-64years than those without symptoms (OR 1.47 (1.10 to 1.96)). Similar results were observed for awareness of hypertension (OR 2.00 (1.30 to 3.06)). Conversely, no associations were found with clinically ascertained hypertension. The act of labelling someone as hypertensive at age 53years was associated with affective symptoms at age 60-64years, independently of antihypertensive treatment and affective symptoms at the time of the diagnosis (OR 2.40 (1.32 to 4.36)).Our findings suggest that elevated risk of hypertension in participants with affective symptoms might be explained by awareness of hypertension and by exposure to medical attention, though not by a direct effect of affective symptoms on blood pressure. Conversely, long-term psychological consequences of the label of hypertension are observed.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

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By the author/editor: Tikhonoff, Valér ...; Hardy, Rebecca; Deanfield, John; Friberg, Peter, ...; Muniz, Graciela; Kuh, Diana; show more...; Pariante, Carmin ...; Hotopf, Matthew; Richards, Marcus; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

Articles in the publication: Open heart

By the university: University of Gothenburg

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