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Influence of indomethacin on the regeneration of cortical bone within titanium implants in rabbits.

Sennerby, Lars, 1960 (author)
Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
Kälebo, Peter (author)
Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för radiologi,Institute of Selected Clinical Sciences, Department of Radiology
Thomsen, Peter, 1953 (author)
Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för biomaterialvetenskap,Institute of Surgical Sciences, Department of Biomaterials
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Albrektsson, Tomas, 1945 (author)
Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för biomaterialvetenskap,Institute of Surgical Sciences, Department of Biomaterials
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 (creator_code:org_t)
Elsevier BV, 1993
1993
English.
In: Biomaterials. - : Elsevier BV. - 0142-9612. ; 14:2, s. 156-8
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The influence of indomethacin on cortical bone regeneration was studied in bone harvest chambers made of commercially pure titanium and inserted in rabbit tibia. Newly formed bone was harvested in situ every 3 wk for 33 wk. Indomethacin (1 mg/kg body weight) was given daily as subcutaneous injections for two periods, followed by two control periods with no drug administration and the same schedule was followed for indomethacin at a dose of 4 mg/kg body weight. These indomethacin dosages did not statistically influence the cortical bone regeneration.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine (hsv//eng)

Keyword

Analysis of Variance
Animals
Densitometry
Female
Indomethacin
pharmacology
Male
Microradiography
Osseointegration
drug effects
Prostheses and Implants
Rabbits
Tibia
Titanium

Publication and Content Type

ref (subject category)
art (subject category)

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Sennerby, Lars, ...
Kälebo, Peter
Thomsen, Peter, ...
Albrektsson, Tom ...
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
Articles in the publication
Biomaterials
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University of Gothenburg

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