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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002997naa a2200313 4500
001oai:gup.ub.gu.se/288695
003SwePub
008240910s1976 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/2886952 URI
024a https://doi.org/10.1113/jphysiol.1976.sp0114312 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Jankowska, Elzbietau Gothenburg University,Göteborgs universitet,Fysiologiska institutionen,Department of Physiology4 aut0 (Swepub:gu)xjanel
2451 0a Disynaptic inhibition of spinal motoneurones from the motor cortex in the monkey.
264 c 1976-06-01
264 1b Wiley,c 1976
520 a 1. The neuronal mechanism of disynaptic inhibition of spinal motoneurones by the corticospinal tract was investigated in Macaca irus. Surface stimulation or weak intracortical stimulation was used in order to evoke the inhibition. Intracellular records were taken from motoneurones in lumbar segments. 2. Both the disynaptic i.p.s.p.s evoked from group Ia afferents and the disynaptic i.p.s.p.s evoked from corticospinal fibres were found to be depressed by conditioning stimulation of motor axons to antagonistic muscles. Mutual facilitation of the actions from these two fibre systems occurred when nerve impulses set up in them reached the explored spinal segment synchronously. These observations led to the conclusion that disynaptic i.p.s.p.s from group Ia afferents and from the motor cortex are mediated by common interneurones. 3. No evidence either for or against projections of the same pyramidal tract cells to motoneurones of one motor nucleus and to interneurones interposed between group Ia afferents and motoneurones of an antagonistic muscle could be obtained by comparing cortical areas from which monosynaptic e.p.s.p.s and disynaptic i.p.s.p.s were evoked in the different motor nuclei. 4. The areas from which the disynaptic i.p.s.p.s were evoked in individual motoneurones appeared to be similar in size to the areas of cortical monosynaptic projections to motoneurones and showed similar degrees of overlap, indicating that the projections of pyramidal tract cells to Ia inhibitory interneurones are as extensive as to motoneurones and that they are similarly organized. © 1976 The Physiological Society
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaper0 (SwePub)3012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicine0 (SwePub)3012 hsv//eng
700a Padel, Y.4 aut
700a Tanaka, R.4 aut
710a Göteborgs universitetb Fysiologiska institutionen4 org
773t The Journal of Physiologyd : Wileyg 258, s. 467-487q 258<467-487x 0022-3751x 1469-7793
856u https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308987
8564 8u https://gup.ub.gu.se/publication/288695
8564 8u https://doi.org/10.1113/jphysiol.1976.sp011431

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