id:"swepub:oai:gup.ub.gu.se/291564"
Sökning: id:"swepub:oai:gup.ub.gu.se/291564" > Effect of delay bet...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04918naa a2200565 4500 | |
| 001 | oai:gup.ub.gu.se/291564 | |
| 003 | SwePub | |
| 008 | 240528s2020 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:43ff29c7-8680-4225-a688-ce61f4384f92 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2915642 URI |
| 024 | 7 | a https://doi.org/10.1002/bjs.114602 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/43ff29c7-8680-4225-a688-ce61f4384f922 URI |
| 040 | a (SwePub)gud (SwePub)lu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Moncrieff, M. D.u University of East Anglia,Norfolk and Norwich University Hospital NHS Trust4 aut |
| 245 | 1 0 | a Effect of delay between nuclear medicine scanning and sentinel node biopsy on outcome in patients with cutaneous melanoma |
| 264 | c 2020-02-19 | |
| 264 | 1 | b Oxford University Press (OUP),c 2020 |
| 520 | a Background Sentinel lymph node biopsy (SLNB) is an important staging tool for the management of melanoma. A multicentre study was done to validate previous findings that the timing of lymphoscintigraphy influences the accuracy of SLNB and patient outcomes, particularly survival. Methods Data were reviewed on patients undergoing SLNB for melanoma at three centres in the UK and Sweden, examining the effect of timing of SLNB after nuclear medicine scanning. Kaplan-Meier survival analysis was used to assess overall (OS), disease-specific (DSS) and progression-free (PFS) survival, stratified by timing of lymphoscintigraphy. Independent risk factors for survival were identified by Cox multivariable regression analysis. Results A total of 2270 patients were identified. Median follow-up was 56 months. Univariable analysis showed a 4 center dot 2 per cent absolute and 35 center dot 5 per cent relative benefit in DSS (hazard ratio 1 center dot 36, 95 per cent c.i. 1 center dot 05 to 1 center dot 74; P = 0 center dot 018) for 863 patients whose SLNB was performed up to 12 h after lymphoscintigraphy compared with 1407 patients who had surgery after more than 12 h. There were similar OS and PFS benefits (P = 0 center dot 036 and P = 0 center dot 022 respectively). Multivariable analysis identified timing of lymphoscintigraphy as an independent predictor of OS (P = 0 center dot 017) and DSS (P = 0 center dot 030). There was an excess of nodal recurrences as first site of recurrence in the group with delayed surgery (4 center dot 5 versus 2 center dot 5 per cent; P = 0 center dot 008). Conclusion Delaying SLNB beyond 12 h after lymphoscintigraphy with Tc-99-labelled nanocolloid has a significant negative survival impact in patients with melanoma. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 653 | a american joint committee | |
| 653 | a intraoperative gamma-probe | |
| 653 | a breast-cancer | |
| 653 | a lymph-nodes | |
| 653 | a mitotic rate | |
| 653 | a lymphoscintigraphy | |
| 653 | a identification | |
| 653 | a metastasis | |
| 653 | a validation | |
| 653 | a age | |
| 653 | a Surgery | |
| 700 | 1 | a O'Leary, F. M.u Norfolk and Norwich University Hospital NHS Trust4 aut |
| 700 | 1 | a Beadsmoore, C. J.u Norfolk and Norwich University Hospital NHS Trust4 aut |
| 700 | 1 | a Pawaroo, D.u Norfolk and Norwich University Hospital NHS Trust4 aut |
| 700 | 1 | a Heaton, M. J.u Norfolk and Norwich University Hospital NHS Trust4 aut |
| 700 | 1 | a Isaksson, K.u Lund University,Lunds universitet,Lunds Melanomstudiegrupp,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund Melanoma Study Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital4 aut0 (Swepub:lu)kir-kis |
| 700 | 1 | a Olofsson Bagge, Roger,d 1978u University of Gothenburg,Gothenburg University,Göteborgs universitet,Wallenberg Centre for Molecular and Translational Medicine,Sahlgrenska University Hospital4 aut0 (Swepub:gu)xoloro |
| 710 | 2 | a University of East Angliab Norfolk and Norwich University Hospital NHS Trust4 org |
| 773 | 0 | t British Journal of Surgeryd : Oxford University Press (OUP)x 0007-1323x 1365-2168 |
| 856 | 4 | u https://academic.oup.com/bjs/article-pdf/107/6/669/35704029/bjs11460.pdf |
| 856 | 4 | u http://dx.doi.org/10.1002/bjs.11460y FULLTEXT |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/291564 |
| 856 | 4 8 | u https://doi.org/10.1002/bjs.11460 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/43ff29c7-8680-4225-a688-ce61f4384f92 |
Hitta via bibliotek
- British Journal of Surgery (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Moncrieff, M. D.
- O'Leary, F. M.
- Beadsmoore, C. J ...
- Pawaroo, D.
- Heaton, M. J.
- Isaksson, K.
- visa fler...
- Olofsson Bagge, ...
- visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Kirurgi
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Cancer och onkol ...
- Artiklar i publikationen
- British Journal ...
- Av lärosätet
- Göteborgs universitet
- Lunds universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
