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Clinical management of patients with genetic obesity during COVID-19 pandemic: position paper of the ESE Growth & Genetic Obesity COVID-19 Study Group and Rare Endo-ERN main thematic group on Growth and Obesity
- De Groot, C. J. (author)
- Bernert, C. P. (author)
- Coupaye, M. (author)
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- Clement, K. (author)
- Paschou, S. A. (author)
- Charmandari, E. (author)
- Kanaka-Gantenbein, C. (author)
- Wabitsch, M. (author)
- Buddingh, E. P. (author)
- Nieuwenhuijsen, B. (author)
- Marina, L. (author)
- Van den Akker, E. L. T. (author)
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- (creator_code:org_t)
- 2021-01-29
- 2021
- English.
- In: Endocrine. - : Springer Science and Business Media LLC. - 1355-008X .- 1559-0100. ; 71, s. 653-662
- Journal article (peer-reviewed)
Abstract
Subject headings
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- This article aims to provide guidance on prevention and treatment of COVID-19 in patients with genetic obesity. Key principals of the management of patients with genetic obesity during COVID-19 pandemic for patients that have contracted COVID-19 are to be aware of: possible adrenal insufficiency (e.g., POMC deficiency, PWS); a more severe course in patients with concomitant immunodeficiency (e.g., LEP and LEPR deficiency), although defective leptin signalling could also be protective against the pro-inflammatory phenotype of COVID-19; disease severity being masked by insufficient awareness of symptoms in syndromic obesity patients with intellectual deficit (in particular PWS); to adjust medication dose to increased body size, preferably use dosing in m2; the high risk of malnutrition in patients with Sars-Cov2 infection, even in case of obesity. Key principals of the obesity management during the pandemic are to strive for optimal obesity management and a healthy lifestyle within the possibilities of the regulations to prevent weight (re)gain and to address anxiety within consultations, since prevalence of anxiety for COVID-19 is underestimated.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Monogenic obesity
- Genetic obesity
- Obesity syndrome
- COVID-19
- SARS-CoV-2
- Endocrinology & Metabolism
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- ref (subject category)
- art (subject category)
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- De Groot, C. J.
- Bernert, C. P.
- Coupaye, M.
- Clement, K.
- Paschou, S. A.
- Charmandari, E.
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- Kanaka-Gantenbei ...
- Wabitsch, M.
- Buddingh, E. P.
- Nieuwenhuijsen, ...
- Marina, L.
- Johannsson, Gudm ...
- Van den Akker, E ...
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- MEDICAL AND HEALTH SCIENCES
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- Articles in the publication
- Endocrine
- By the university
- University of Gothenburg
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