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Sökning: id:"swepub:oai:gup.ub.gu.se/307127" > Cardiovascular biom...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005952naa a2200637 4500
001oai:gup.ub.gu.se/307127
003SwePub
008240528s2021 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-446785
0247 a https://gup.ub.gu.se/publication/3071272 URI
0247 a https://doi.org/10.1093/ehjacc/zuab0092 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4467852 URI
040 a (SwePub)gud (SwePub)uu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Mueller, C.u Univ Basel, Univ Hosp Basel, Dept Cardiol, Petersgraben 4, CH-4031 Basel, Switzerland.;Univ Basel, Univ Hosp Basel, Cardiovasc Res Inst Basel, Petersgraben 4, CH-4031 Basel, Switzerland.4 aut
2451 0a Cardiovascular biomarkers in patients with COVID-19
264 c 2021-02-28
264 1b Oxford University Press (OUP),c 2021
520 a The coronavirus disease 2019 (COVID-19) pandemic has increased awareness that severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2) may have profound effects on the cardiovascular system. COVID-19 often affects patients with pre-existing cardiac disease, and may trigger acute respiratory distress syndrome (ARDS), venous thromboembolism (VTE), acute myocardial infarction (AMI), and acute heart failure (AHF). However, as COVID-19 is primarily a respiratory infectious disease, there remain substantial uncertainty and controversy whether and how cardiovascular biomarkers should be used in patients with suspected COVID-19. To help clinicians understand the possible value as well as the most appropriate interpretation of cardiovascular biomarkers in COVID-19, it is important to highlight that recent findings regarding the prognostic role of cardiovascular biomarkers in patients hospitalized with COVID-19 are similar to those obtained in studies for pneumonia and ARDS in general. Cardiovascular biomarkers reflecting pathophysiological processes involved in COVID-19/pneumonia and its complications have a role evaluating disease severity, cardiac involvement, and risk of death in COVID-19 as well as in pneumonias caused by other pathogens. First, cardiomyocyte injury, as quantified by cardiac troponin concentrations, and haemodynamic cardiac stress, as quantified by natriuretic peptide concentrations, may occur in COVID-19 as in other pneumonias. The level of those biomarkers correlates with disease severity and mortality. Interpretation of cardiac troponin and natriuretic peptide concentrations as quantitative variables may aid in risk stratification in COVID-19/pneumonia and also will ensure that these biomarkers maintain high diagnostic accuracy for AMI and AHF. Second, activated coagulation as quantified by D-dimers seems more prominent in COVID-19 as in other pneumonias. Due to the central role of endothelitis and VTE in COVID-19, serial measurements of D-dimers may help physicians in the selection of patients for VTE imaging and the intensification of the level of anticoagulation from prophylactic to slightly higher or even therapeutic doses.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a COVID-19
653 a Biomarkers
653 a Cardiac troponin
653 a Natriuretic peptides
653 a D-dimer
653 a Risk prediction
653 a natriuretic peptide
653 a cardiac troponin
653 a risk
653 a stroke
653 a Cardiovascular System & Cardiology
653 a COVID-19
7001 a Giannitsis, E.u Heidelberg Univ, Dept Cardiol, Heidelberg, Germany.4 aut
7001 a Jaffe, A. S.u Mayo Clin & Mayo Grad Sch Med, Rochester, MN USA.4 aut
7001 a Huber, K.u Wilhelminenhospital, Dept Med Cardiol & Intens Care Med, Vienna, Austria.;Sigmund Freud Univ, Med Sch, Vienna, Austria.4 aut
7001 a Mair, J.u Med Univ Innsbruck, Dept Internal Med Cardiol & Angiol 3, Innsbruck, Austria.4 aut
7001 a Cullen, L.u Univ Queensland, Royal Brisbane & Womens Hosp, Emergency & Trauma Ctr, St Lucia, Qld, Australia.4 aut
7001 a Hammarsten, Olau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin,Institute of Biomedicine,Univ Gothenburg, Dept Clin Chem & Transfus Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xhamol
7001 a Mills, N. L.u Univ Edinburgh, Univ BHF Ctr Cardiovasc Sci, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Usher Inst, Edinburgh, Midlothian, Scotland.4 aut
7001 a Mockel, M.u Charite Univ Med Berlin, Div Emergency Med, Berlin, Germany.4 aut
7001 a Krychtiuk, K.u Med Univ Vienna, Dept Internal Med 2, Div Cardiol, Vienna, Austria.4 aut
7001 a Thygesen, K.u Aarhus Univ Hosp, Dept Cardiol, Aarhus, Denmark.4 aut
7001 a Lindahl, Bertil,d 1957-u Uppsala universitet,Kardiologi4 aut0 (Swepub:uu)belin227
7001 a Acute Cardiovasc Care, Assoc4 aut
7102 a Univ Basel, Univ Hosp Basel, Dept Cardiol, Petersgraben 4, CH-4031 Basel, Switzerland.;Univ Basel, Univ Hosp Basel, Cardiovasc Res Inst Basel, Petersgraben 4, CH-4031 Basel, Switzerland.b Heidelberg Univ, Dept Cardiol, Heidelberg, Germany.4 org
7730 t European Heart Journal-Acute Cardiovascular Cared : Oxford University Press (OUP)g 10:3, s. 310-319q 10:3<310-319x 2048-8726x 2048-8734
8564 u https://academic.oup.com/ehjacc/article-pdf/10/3/310/39211523/zuab009.pdf
8564 8u https://gup.ub.gu.se/publication/307127
8564 8u https://doi.org/10.1093/ehjacc/zuab009
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-446785

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