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Costs associated with retinopathy of prematurity: a systematic review and meta-analysis.

Gyllensten, Hanna, 1979 (author)
Gothenburg University,Göteborgs universitet,Centrum för personcentrerad vård vid Göteborgs universitet (GPCC),Institutionen för vårdvetenskap och hälsa,University of Gothenburg Centre for person-centred care (GPCC),Institute of Health and Care Sciences
Humayun, Jhangir (author)
Gothenburg University,Göteborgs universitet,Centrum för personcentrerad vård vid Göteborgs universitet (GPCC),Institutionen för vårdvetenskap och hälsa,University of Gothenburg Centre for person-centred care (GPCC),Institute of Health and Care Sciences
Sjöbom, Ulrika (author)
Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Health and Care Sciences,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
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Hellström, Ann, 1959 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
Löfqvist, Chatarina, 1964 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Centrum för personcentrerad vård vid Göteborgs universitet (GPCC),Institutionen för vårdvetenskap och hälsa,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,University of Gothenburg Centre for person-centred care (GPCC),Institute of Health and Care Sciences
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 (creator_code:org_t)
2022-11-24
2022
English.
In: BMJ open. - : BMJ. - 2044-6055. ; 12:11
  • Research review (peer-reviewed)
Abstract Subject headings
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  • To review and analyse evidence regarding costs for retinopathy of prematurity (ROP) screening, lifetime costs and resource use among infants born preterm who develop ROP, and how these costs have developed over time in different regions.Systematic review and meta-analysis DATA SOURCES: PubMed and Scopus from inception to 23 June 2021.Included studies presented costs for ROP screening and the lifetime costs (including laser treatment and follow-up costs) and resource use among people who develop ROP. Studies not reporting on cost calculation methods or ROP-specific costs were excluded.Two independent reviewers screened for inclusion and extracted data, including items from a published checklist for quality assessment used for bias assessment, summary and random-effects meta-analysis for treatment costs. Included studies were further searched to identify eligible references and citations.In total, 15 studies reported ROP screening costs, and 13 reported lifetime costs (either treatment and/or follow-up costs) for infants with ROP. The range for screening costs (10 studies) was US$5-US$253 per visit, or US$324-US$1072 per screened child (5 studies). Costs for treatment (11 studies) ranged from US$38 to US$6500 per child. Four studies reported healthcare follow-up costs (lifetime costs ranging from US$64 to US$2420, and 10-year costs of US$1695, respectively), and of these, three also reported lifetime costs for blindness (range US$26 686-US$224 295) using secondary cost data. Included papers largely followed the quality assessment checklist items, thus indicating a low risk of bias.The costs of screening for and treating ROP are small compared with the societal costs of resulting blindness. However, little evidence is available for predicting the effects of changes in patient population, screening schedule or ROP treatments.CRD42020208213.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Oftalmologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Ophthalmology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)

Keyword

Infant
Newborn
Infant
Child
Humans
Retinopathy of Prematurity
therapy
Health Care Costs
Blindness
etiology

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Gyllensten, Hann ...
Humayun, Jhangir
Sjöbom, Ulrika
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