Sökning: id:"swepub:oai:gup.ub.gu.se/325012" > Radiographic damage...
Fältnamn | Indikatorer | Metadata |
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000 | 05900naa a2200673 4500 | |
001 | oai:gup.ub.gu.se/325012 | |
003 | SwePub | |
008 | 240910s2023 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:450aca49-463b-44b5-b1cd-83d767398a3d | |
024 | 7 | a https://gup.ub.gu.se/publication/3250122 URI |
024 | 7 | a https://doi.org/10.1186/s13075-023-03015-92 DOI |
024 | 7 | a https://lup.lub.lu.se/record/450aca49-463b-44b5-b1cd-83d767398a3d2 URI |
040 | a (SwePub)gud (SwePub)lu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Eberhard, Annau Lund University,Lunds universitet,Reumatologi,Forskargrupper vid Lunds universitet,Rheumatology,Lund University Research Groups,Helsingborg Hospital4 aut0 (Swepub:lu)an6316eb |
245 | 1 0 | a Radiographic damage in early rheumatoid arthritis is associated with increased disability but not with pain-a 5-year follow-up study |
264 | c 2023-02-27 | |
264 | 1 | b Springer Science and Business Media LLC,c 2023 |
520 | a ObjectivesTo evaluate how radiographic damage, overall and measured as joint space narrowing score (JSNS) and erosion score (ES), as well as other clinical and laboratory measures, relate to disability and pain in early rheumatoid arthritis (RA).MethodsAn inception cohort of 233 patients with early RA, recruited in 1995-2005, was followed for 5 years. Disability was assessed with the Health Assessment Questionnaire (HAQ), and pain with a visual analogue scale (VAS; 0-100 mm). Radiographs of hands and feet were evaluated using the Sharp-van der Heijde score (SHS), including JSNS and ES. The relation for radiographic scores and other clinical parameters with pain and HAQ were evaluated cross-sectionally by multivariate linear regression analysis and over time using generalized estimating equations.ResultsES was significantly associated with HAQ cross-sectionally at inclusion, after 2 and after 5 years, and over time. Associations for HAQ with SHS and JSNS were weaker and less consistent compared with those for ES. There was no association between radiographic scores and pain at any visit. Both HAQ and pain were associated with parameters of disease activity. The strongest cross-sectional associations were found for the number of tender joints (adjusted p<0.001 at all visits).ConclusionJoint damage was associated with disability already in early RA. Erosions of hands and feet appear to have a greater influence on disability compared with joint space narrowing early in the disease. Pain was associated with other factors than joint destruction in early RA, in particular joint tenderness-suggesting an impact of pain sensitization. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng |
653 | a Rheumatoid arthritis | |
653 | a Pain | |
653 | a Disability | |
653 | a Radiographic damage | |
653 | a disease-activity | |
653 | a physical function | |
653 | a joint damage | |
653 | a functional | |
653 | a disability | |
653 | a classification | |
653 | a progression | |
653 | a impairment | |
653 | a predictors | |
653 | a depression | |
653 | a criteria | |
653 | a Rheumatology | |
653 | a Humans | |
653 | a Follow-Up Studies | |
653 | a Cross-Sectional Studies | |
653 | a Arthritis, Rheumatoid/complications | |
653 | a Pain/diagnostic imaging | |
653 | a Arthralgia | |
700 | 1 | a Rydell, Emilu Lund University,Lunds universitet,Reumatologi,Forskargrupper vid Lunds universitet,Rheumatology,Lund University Research Groups4 aut0 (Swepub:lu)em5271ry |
700 | 1 | a Forslind, Kristinau Lund University,Lunds universitet,Spenshults artrit grupp,Forskargrupper vid Lunds universitet,Spenshults arthritis group,Lund University Research Groups,Spenshult Research and Development Center4 aut0 (Swepub:lu)med-kfi |
700 | 1 | a Bergman, Stefanu University of Gothenburg,Lund University,Lunds universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Spenshults artrit grupp,Forskargrupper vid Lunds universitet,Spenshults arthritis group,Lund University Research Groups,Spenshult Research and Development Center4 aut0 (Swepub:lu)med-seb |
700 | 1 | a Mandl, Thomasu Lund University,Lunds universitet,Reumatologi,Forskargrupper vid Lunds universitet,Rheumatology,Lund University Research Groups4 aut0 (Swepub:lu)medf-tma |
700 | 1 | a Olofsson, Toru Lund University,Lunds universitet,Reumatologi,Forskargrupper vid Lunds universitet,Rheumatology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)efor-tol |
700 | 1 | a Jacobsson, Lennart T. H.,d 1954u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research,Sahlgrenska Academy4 aut0 (Swepub:lu)orto-lja |
700 | 1 | a Turesson, Carlu Lund University,Lunds universitet,Reumatologi,Forskargrupper vid Lunds universitet,Rheumatology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-ctn |
710 | 2 | a Reumatologib Forskargrupper vid Lunds universitet4 org |
773 | 0 | t Arthritis Research & Therapyd : Springer Science and Business Media LLCg 25:1q 25:1x 1478-6354x 1478-6362 |
856 | 4 | u http://dx.doi.org/10.1186/s13075-023-03015-9x freey FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/325012 |
856 | 4 8 | u https://doi.org/10.1186/s13075-023-03015-9 |
856 | 4 8 | u https://lup.lub.lu.se/record/450aca49-463b-44b5-b1cd-83d767398a3d |
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