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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005115naa a2200565 4500
001oai:gup.ub.gu.se/334002
003SwePub
008240528s2023 | |||||||||||000 ||eng|
009oai:DiVA.org:liu-194169
0247 a https://gup.ub.gu.se/publication/3340022 URI
0247 a https://doi.org/10.1186/s12875-023-02063-z2 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1941692 URI
040 a (SwePub)gud (SwePub)liu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Holtedahl, Knutu UiT Arctic Univ Norway, Norway4 aut
2451 0a Symptoms and signs of urogenital cancer in primary care
264 1b BMC,c 2023
520 a BACKGROUND: Urogenital cancers are common, accounting for approximately 20% of cancer incidence globally. Cancers belonging to the same organ system often present with similar symptoms, making initial management challenging. In this study, 511 cases of cancer were recorded after the date of consultation among 61,802 randomly selected patients presenting in primary care in six European countries: a subgroup analysis of urogenital cancers was carried out in order to study variation in symptom presentation. METHODS: Initial data capture was by completion of standardised forms containing closed questions about symptoms recorded during the consultation. The general practitioner (GP) provided follow-up data after diagnosis, based on medical record data made after the consultation. GPs also provided free text comments about the diagnostic procedure for individual patients. RESULTS: The most common symptoms were mainly associated with one or two specific types of cancer: 'Macroscopic haematuria' with bladder or renal cancer (combined sensitivity 28.3%), 'Increased urinary frequency' with bladder (sensitivity 13.3%) or prostatic (sensitivity 32.1%) cancer, or to uterine body (sensitivity 14.3%) cancer, 'Unexpected genital bleeding' with uterine cancer (cervix, sensitivity 20.0%, uterine body, sensitivity 71.4%). 'Distended abdomen, bloating' had sensitivity 62.5% (based on eight cases of ovarian cancer). In ovarian cancer, increased abdominal circumference and a palpable tumour also were important diagnostic elements. Specificity for 'Macroscopic haematuria' was 99.8% (99.7-99.8). PPV>3% was noted for 'Macroscopic haematuria' and bladder or renal cancer combined, for bladder cancer in male patients. In males aged 55-74, PPV=7.1% for 'Macroscopic haematuria' and bladder cancer. Abdominal pain was an infrequent symptom in urogenital cancers. CONCLUSIONS: Most types of urogenital cancer present with rather specific symptoms. If the GP considers ovarian cancer, increased abdominal circumference should be actively determined. Several cases were clarified through the GP's clinical examination, or laboratory investigations.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a Bladder cancer
653 a Cervical cancer
653 a General practice
653 a Neoplasms
653 a Ovarian cancer
653 a Primary health care
653 a Prostate cancer
653 a Renal cancer
653 a Urogenital cancer
653 a Uterine body cancer
653 a Neoplasms; Urogenital cancer; Bladder cancer; Renal cancer; Prostate cancer; Cervical cancer; Uterine body cancer; Ovarian cancer; General practice; Primary health care
7001 a Borgquist, Larsu Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten4 aut0 (Swepub:liu)larbo78
7001 a Donker, Gé A.u Netherlands Inst Hlth Serv Res, Netherlands4 aut
7001 a Buntinx, Franku Katholieke Univ Leuven, Belgium; Maastricht Univ, Netherlands4 aut
7001 a Weller, Davidu Univ Edinburgh, Scotland4 aut
7001 a Campbell, Christineu Univ Edinburgh, Scotland4 aut
7001 a Månsson, Jörgen,d 1958u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sweden4 aut0 (Swepub:gu)xmansj
7001 a Hammersley, Victoriau Univ Edinburgh, Scotland4 aut
7001 a Braaten, Tonjeu UiT Arctic Univ Norway, Norway4 aut
7001 a Parajuli, Ranjanu Independent researcher, Tromsø, Norway4 aut
7102 a UiT Arctic Univ Norway, Norwayb Avdelningen för prevention, rehabilitering och nära vård4 org
7730 t BMC primary cared : BMCg 24:1q 24:1x 2731-4553
8564 u https://doi.org/10.1186/s12875-023-02063-zy Fulltext
8564 u https://liu.diva-portal.org/smash/get/diva2:1760522/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://gup.ub.gu.se/publication/334002
8564 8u https://doi.org/10.1186/s12875-023-02063-z
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-194169

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