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A follow-up study o...
A follow-up study of Nordic multiple sclerosis candidate gene regions
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Datta, P. (author)
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Harbo, HF (author)
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Ryder, LP (author)
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Akesson, E (author)
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Benedikz, J (author)
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Celius, EG (author)
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- Andersen, Oluf, 1941 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
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Myhe, KM (author)
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- Sandberg Wollheim, Magnhild (author)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Hillert, J (author)
- Karolinska Institutet
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Svejgaard, A (author)
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Sorensen, PS (author)
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Spurkland, A (author)
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Oturai, A (author)
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(creator_code:org_t)
- 2007-02-16
- 2007
- English.
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In: MULTIPLE SCLEROSIS. - : SAGE Publications. - 1352-4585 .- 1477-0970. ; 13:5, s. 584-589
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Abstract
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- In this study, the results from three Nordic linkage disequilibrium screens in multiple sclerosis (MS) were investigated, in a new sample set of 314 Nordic MS trios from Denmark, Norway, Sweden and Iceland. Among 30 non-HLA and two HLA microsatellite markers individually genotyped, eight markers displayed distorted transmission with uncorrected P-value <0.05, ranked in this order: D6S2443 (6p21.32, HLA class II) (P corrected =0.01), D2S2201 (2p24), D19S552 (19q13), D3S3584 (3q21), D17S975 (17q11), D1S2627 (1p22), D6S273 (6p21.33, HLA class III) and D12S1051 (12q23). These non-HLA regions need further investigation as possible MS candidate gene regions in our population. Multiple Sclerosis 2007; 13: 584-589. http://msj.sagepub.com
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- linkage disequilibrium
- diagnostic-criteria
- chromosome 19q13
- genome screen
- association
- susceptibility
- guidelines
- errors
- sclerosis
- Nordic countries
- multiple
- LID screens
- HLA
- genetics
- candidate regions
- GAMES
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Datta, P.
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Harbo, HF
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Ryder, LP
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Akesson, E
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Benedikz, J
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Celius, EG
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show more...
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Andersen, Oluf, ...
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Myhe, KM
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Sandberg Wollhei ...
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Hillert, J
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Svejgaard, A
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Sorensen, PS
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Spurkland, A
-
Oturai, A
-
show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Neurology
- Articles in the publication
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MULTIPLE SCLEROS ...
- By the university
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University of Gothenburg
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Lund University
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Karolinska Institutet