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Sökning: id:"swepub:oai:lup.lub.lu.se:03fd1465-0a98-4519-bb5d-19bf15279056" > Short-Term Diabetes...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003615naa a2200289 4500
001oai:lup.lub.lu.se:03fd1465-0a98-4519-bb5d-19bf15279056
003SwePub
008160401s2008 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/12893582 URI
024a https://doi.org/10.1109/IEMBS.2008.46491472 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a kon2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Ståhl, Fredriku Lund University,Lunds universitet,Institutionen för reglerteknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Automatic Control,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)cont-fsl
2451 0a Short-Term Diabetes Blood Glucose Prediction Based on Blood Glucose Measurements
264 1c 2008
520 a Insulin Dependent Diabetes Mellitus (IDDM) is a chronic disease characterized by the inability of the pancreas to produce sufficient amounts of insulin. Daily compensation of the deficiency requires 4-6 insulin injections to be taken daily, the aim of this insulin therapy being to maintain normoglycemia- i.e., a blood glucose level between 4-7 mmol/L. To determine the quantity and timing of these injections, various different approaches are used. Currently, mostly qualitative and semi-quantitative models and reasoning are used to design such a therapy. Here, an attempt is made to show how system identification and control may be used to estimate predictive quantitative models to be used in design of optimal insulin regimens. The system was divided into three subsystems, the insulin subsystem, the glucose subsystem and the insulin-glucose interaction. The insulin subsystem aims to describe the absorbtion of injected insulin from the subcutaneous depots and the glucose subsystem the absorbtion of glucose from the gut following a meal. These subsystems were modeled using compartment models and proposed models found in the literature. Several black-box models and grey-box models describing the insulin/glucose interaction were developed and analysed. These models were fitted to real data monitored by a IDDM patient. Many difficulties were encountered, typical of biomedical systems: Non-uniform and scarce sampling, time-varying dynamics and severe nonlinearities were some of the difficulties encountered during the modeling. None of the proposed models were able to describe the system accurately in all aspects during all conditions. However, all the linear models shared some dynamics. Based on the estimated models, short-term blood glucose predictors for up to two-hour-ahead blood glucose prediction were investigated.
650 7a TEKNIK OCH TEKNOLOGIERx Elektroteknik och elektronikx Reglerteknik0 (SwePub)202022 hsv//swe
650 7a ENGINEERING AND TECHNOLOGYx Electrical Engineering, Electronic Engineering, Information Engineeringx Control Engineering0 (SwePub)202022 hsv//eng
700a Johansson, Rolfu Lund University,Lunds universitet,Institutionen för reglerteknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Automatic Control,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)cont-rjo
710a Institutionen för reglerteknikb Institutioner vid LTH4 org
773t 2008 Annual International Conference of the IEEE Engineering in Medicine and Biology Societyg 1, s. 291-294q 1<291-294x 1557-170Xz 9781424418145
856u http://dx.doi.org/10.1109/IEMBS.2008.4649147y FULLTEXT
8564 8u https://lup.lub.lu.se/record/1289358
8564 8u https://doi.org/10.1109/IEMBS.2008.4649147

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Ståhl, Fredrik
Johansson, Rolf
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TEKNIK OCH TEKNOLOGIER
TEKNIK OCH TEKNO ...
och Elektroteknik oc ...
och Reglerteknik
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2008 Annual Inte ...
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Lunds universitet

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