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Development of Curative Therapies for Ewing Sarcomas by Interdisciplinary Cooperative Groups in Europe.
- Bölling, T (author)
- Braun-Munzinger, G (author)
- Burdach, S (author)
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- Calaminus, G (author)
- Craft, A (author)
- Delattre, O (author)
- Deley, M-C L (author)
- Dirksen, U (author)
- Dockhorn-Dworniczak, B (author)
- Dunst, J (author)
- Engel, S (author)
- Faldum, A (author)
- Fröhlich, B (author)
- Gadner, H (author)
- Göbel, U (author)
- Gosheger, G (author)
- Hardes, J (author)
- Hawkins, D S (author)
- Hoffmann, C (author)
- Kovar, H (author)
- Kruseova, J (author)
- Ladenstein, R (author)
- Leuschner, I (author)
- Lewis, I J (author)
- Oberlin, O (author)
- Paulussen, M (author)
- Potratz, J (author)
- Ranft, A (author)
- Rössig, C (author)
- Rübe, C (author)
- Sauer, R (author)
- Schober, O (author)
- Schuck, A (author)
- Timmermann, B (author)
- Tirode, F (author)
- van den Berg, H (author)
- van Valen, F (author)
- Vieth, V (author)
- Willich, N (author)
- Winkelmann, W (author)
- Whelan, J (author)
- Womer, R B (author)
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- (creator_code:org_t)
- 2015-05-18
- 2015
- English.
- In: Klinische Pädiatrie. - : Georg Thieme Verlag KG. - 1439-3824 .- 0300-8630. ; 227:3, s. 108-115
- Research review (peer-reviewed)
Abstract
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- Curative therapies for Ewing sarcoma have been developed within cooperative groups. Consecutive clinical trials have systematically assessed the impact and timing of local therapy and the activity of cytotoxic drugs and their combinations. They have led to an increase of long-term disease-free survival to around 70% in patients with localized disease. Translational research in ES remains an area in which interdisciplinary and international cooperation is essential for future progress. This article reviews current state-of-the art therapy, with a focus on trials performed in Europe, and summarizes novel strategies to further advance both the cure rates and quality of survival.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
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- Bölling, T
- Braun-Munzinger, ...
- Burdach, S
- Calaminus, G
- Craft, A
- Delattre, O
- show more...
- Deley, M-C L
- Dirksen, U
- Dockhorn-Dwornic ...
- Dunst, J
- Engel, S
- Faldum, A
- Fröhlich, B
- Gadner, H
- Göbel, U
- Gosheger, G
- Hardes, J
- Hawkins, D S
- Hjorth, Lars
- Hoffmann, C
- Kovar, H
- Kruseova, J
- Ladenstein, R
- Leuschner, I
- Lewis, I J
- Oberlin, O
- Paulussen, M
- Potratz, J
- Ranft, A
- Rössig, C
- Rübe, C
- Sauer, R
- Schober, O
- Schuck, A
- Timmermann, B
- Tirode, F
- van den Berg, H
- van Valen, F
- Vieth, V
- Willich, N
- Winkelmann, W
- Whelan, J
- Womer, R B
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- MEDICAL AND HEALTH SCIENCES
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- Lund University
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