id:"swepub:oai:lup.lub.lu.se:1ea11472-af66-4952-8d19-0f4d84940098"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02755naa a2200373 4500 | |
| 001 | oai:lup.lub.lu.se:1ea11472-af66-4952-8d19-0f4d84940098 | |
| 003 | SwePub | |
| 008 | 160401s2002 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/3249542 URI |
| 024 | 7 | a https://doi.org/10.1152/japplphysiol.00473.20022 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Allen, G4 aut |
| 245 | 1 0 | a Transient mechanical benefits of a deep inflation in the injured mouse lung |
| 264 | 1 | b American Physiological Society,c 2002 |
| 520 | a The lasting effects of a recruitment maneuver (RM) in the injured lung are not well characterized. We speculated that the reduction in respiratory elastance (H) after a deep inflation (DI) is transient in nature and should be sustained longer at higher positive end-expiratory pressure (PEEP). Thirteen ventilated mice were given 2 DIs at various levels of PEEP before and after saline lavage. Forced oscillations were used to measure H periodically over 7 min after the DIs. Time constants (tau) were estimated for the post-DI recovery in H. Values for tau before lavage (80-115 s) were reduced after lavage (13-30 s) at all levels of PEEP (P = 0.0001). PEEP did not significantly influence tau before or after lavage. The plateau level and total recovery in H after a DI were significantly influenced by PEEP and lavage (P < 0.0001). Our results suggest that for a DI to be beneficial in the injured mouse lung, it may have to be applied several times a minute. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng |
| 653 | a atelectasis | |
| 653 | a recruitment | |
| 653 | a positive-pressure respiration | |
| 653 | a elastance | |
| 653 | a acute lung injury | |
| 700 | 1 | a Lundblad, Lennartu Lund University,Lunds universitet,Klinisk fysiologi och nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Physiology and Nuclear Medicine, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)zoof-llu |
| 700 | 1 | a Parsons, P4 aut |
| 700 | 1 | a Bates, JHT4 aut |
| 710 | 2 | a Klinisk fysiologi och nuklearmedicin, Malmöb Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t Journal of Applied Physiologyd : American Physiological Societyg 93:5, s. 1709-1715q 93:5<1709-1715x 1522-1601x 8750-7587 |
| 856 | 4 | u http://dx.doi.org/10.1152/japplphysiol.00473.2002x freey FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/324954 |
| 856 | 4 8 | u https://doi.org/10.1152/japplphysiol.00473.2002 |
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