Simultaneous detection of molecular oxygen and water vapor in the tissue optical window using tunable diode laser spectroscopy

Persson, Linda (author): Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH

Andersson, Mats (author): Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH

Lewander, Märta (author): Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH

Svanberg, Katarina (author): Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH

Svanberg, Sune (author): Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH

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Abstract Subject headings

We report on a newly developed diode-laser spectroscopic system for gas detection in scattering media. Two pigtailed diode lasers are used, operating in a wavelength modulation scheme, to simultaneously detect molecular oxygen at 760 nm and water vapour at 935 nm within the tissue optical window (600 nm to 1.3 μm). Different modulation frequencies are used to distinguish between the two wavelengths. No crosstalk can be observed between the gas contents of the two gas channels. The system is made compact by using a computer board and performing software based lock-in detection. The noise floor obtained corresponds to an absorption fraction of about 6 · 10−5 for both oxygen and water vapour. The power of the technique is illustrated by preliminary results from a clinical trial investigating the human sinuses.

By the author/editor: Persson, Linda; Andersson, Mats; Lewander, Märta; Svanberg, Katari ...; Svanberg, Sune

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cancer and Oncol ...

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