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Induction of mammar...
Induction of mammary fibroadenomas in rats by adenovirus type 9
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- Ankerst, J. (author)
- Lund University,Lunds universitet,Klinisk lungmedicin,Forskargrupper vid Lunds universitet,Clinical Respiratory Medicine,Lund University Research Groups
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- Jonsson, N. (author)
- Lund University,Lunds universitet,Patologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Pathology, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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Kjellén, L. (author)
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- Norrby, E. (author)
- Karolinska Institute
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- Sjögren, H. O. (author)
- Lund University,Lunds universitet,Wallenberglaboratoriet, Malmö,Medicinska fakulteten,The Wallenberg Laboratory, Malmö,Faculty of Medicine
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(creator_code:org_t)
- Wiley, 1974
- 1974
- English 5 s.
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In: International Journal of Cancer. - : Wiley. - 0020-7136 .- 1097-0215. ; 13:3, s. 286-290
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http://dx.doi.org/10...
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Abstract
Subject headings
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- After inoculation of adenovirus type 9 into newborn Wistar/Furth rats, seven out of seven females developed one or several mammary fibroadenomas within 14–25 weeks after virus inoculation. No tumours were observed in male rats inoculated with the same virus or in untreated controls. Neonatal inoculations of adenovirus type 5, produced on the same HeLa cells, gave negative results in both sexes. The results indicate that benign mammary tumours can be induced in rats by a virus and that mammary fibroadenomas are induced by adenovirus type 9, previously known to be capable of transforming cells in vitro but not of inducing tumours in vivo.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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