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Exact algebraization of the signal equation of spoiled gradient echo MRI

Dathe, Henning (author)
Helms, Gunther (author)
Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
 (creator_code:org_t)
2010-07-08
2010
English.
In: Physics in Medicine and Biology. - : IOP Publishing. - 1361-6560 .- 0031-9155. ; 55, s. 4231-4245
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The Ernst equation for Fourier transform nuclear magnetic resonance (MR) describes the spoiled steady-state signal created by periodic partial excitation. In MR imaging (MRI), it is commonly applied to spoiled gradient-echo acquisition in the steady state, created by a small flip angle α at a repetition time TR much shorter than the longitudinal relaxation time T1. We describe two parameter transformations of α and TR/T1, which render the Ernst equation as a low-order rational function. Computer algebra can be readily applied for analytically solving protocol optimization, as shown for the dual flip angle experiment. These transformations are based on the half-angle tangent substitution and its hyperbolic analogue. They are monotonic and approach identity for small α and small TR/T1 with a third-order error. Thus, the exact algebraization can be readily applied to fast gradient echo MRI to yield a rational approximation in α and TR/T1. This reveals a fundamental relationship between the square of the flip angle and TR/T1 which characterizes the Ernst angle, constant degree of T1-weighting and the influence of the local radiofrequency field.

Subject headings

NATURVETENSKAP  -- Fysik -- Annan fysik (hsv//swe)
NATURAL SCIENCES  -- Physical Sciences -- Other Physics Topics (hsv//eng)
TEKNIK OCH TEKNOLOGIER  -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Medical Engineering -- Medical Image Processing (hsv//eng)

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Dathe, Henning
Helms, Gunther
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