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id:"swepub:oai:lup.lub.lu.se:4c18ef91-780d-43b4-9136-05a2c9b53078"
 

Sökning: id:"swepub:oai:lup.lub.lu.se:4c18ef91-780d-43b4-9136-05a2c9b53078" > Underdosage of the ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003948naa a2200445 4500
001oai:lup.lub.lu.se:4c18ef91-780d-43b4-9136-05a2c9b53078
003SwePub
008160401s2002 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/3332392 URI
024a https://doi.org/10.1118/1.14874212 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Martens, C4 aut
2451 0a Underdosage of the upper-airway mucosa for small fields as used in intensity-modulated radiation therapy: A comparison between radiochromic film measurements, Monte Carlo simulations, and collapsed cone convolution calculations
264 c 2002-06-21
264 1b Wiley,c 2002
520 a Head-and-neck tumors are often situated at an air-tissue interface what may result in an underdosage of part of the tumor in radiotherapy treatments using megavoltage photons. especially for small fields. In addition to effects of transient electronic disequilibrium, for these small fields, an increased lateral electron range in air will result in an important extra reduction of the central axis (lose beyond the cavity. Therefore dose calculation algorithms need to model electron transport accurately. We simulated the trachea by a 2 cm diameter cylindrical air cavity with the rin) situated 2 cm beneath the phantom surface. A 6 MV photon beam from an Elekta SLi plus linear accelerator, equipped with the standard multileaf collimator (MLC), was assessed. A 10 x 2 cm(2) and a 10 K 1 cm(2) field, both widthwise collimated by the MLC, were applied with their long side parallel to the cylinder axis. Central axis dose rebuild-up was studied. Radiochromic film measurements were performed in an in-house manufactured polystyrene phantom with the films oriented either along or perpendicular to the beam axis. Monte Carlo simulations were performed with BEAM and EGSnrc. Calculations were also performed using the pencil beam (PB) algorithm and the collapsed cone convolution (CCC) algorithm of Helax-TMS (MDS Nordion, Kanata. Canada) version 6.0.2 and using the CCC algorithm of Pinnacle (ADAC Laboratories, Milpitas. CA, USA) version 4.2. A very good agreement between the film measurements and the Monte Carlo simulations was found. The CCC algorithms were not able to predict the interface dose accurately when lateral electronic disequilibrium occurs, but were shown to be a considerable improvement compared to the PB algorithm. The CCC algorithms overestimate the dose in the rebuild-up region. The interface dose was overestimated by a maximum of 31% or 54%, depending on the implementation of the CCC algorithm. At a depth of I rum, the maximum dose overestimation was 14% or 24%.
650 7a NATURVETENSKAPx Biologix Biofysik0 (SwePub)106032 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Biophysics0 (SwePub)106032 hsv//eng
653 a collapsed
653 a Monte Carlo
653 a radiochromic film
653 a air cavity
653 a small fields
653 a cone convolution calculations
700a Reynaert, N4 aut
700a De Wagter, C4 aut
700a Nilsson, Peru Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)rafy-per
700a Coghe, M4 aut
700a Palmans, H4 aut
700a Theirens, H4 aut
700a De Neve, W4 aut
710a Medicinsk strålningsfysik, Lundb Sektion V4 org
773t Medical Physicsd : Wileyg 29:7, s. 1528-1535q 29:7<1528-1535x 0094-2405
856u http://dx.doi.org/10.1118/1.1487421y FULLTEXT
8564 8u https://lup.lub.lu.se/record/333239
8564 8u https://doi.org/10.1118/1.1487421

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