Classification of osteoarthritis biomarkers: a proposed approach

Bauer, D. C. (author)

Hunter, D. J. (author)

Abramson, S. B. (author)

Attur, M. (author)

Corr, M. (author)

Felson, D. (author)

Heinegård, Dick (author): Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine

Jordan, J. M. (author)

Kepler, T. B. (author)

Lane, N. E. (author)

Saxne, Tore (author): Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine

Tyree, B. (author)

Kraus, V. B. (author)

(creator_code:org_t)

Elsevier BV, 2006
2006
English.
In: Osteoarthritis and Cartilage. - : Elsevier BV. - 1063-4584. ; 14:8, s. 723-727

Related links:: http://dx.doi.org/10...; show more...; http://www.oarsijour...; https://lup.lub.lu.s...; https://doi.org/10.1...; show less...

Abstract Subject headings

Objective: Osteoarthritis (OA) biomarkers are needed by researchers and clinicians to assist in disease diagnosis and assessment of disease severity, risk of onset, and progression. As effective agents for CA are developed and tested in clinical studies, biomarkers; that reliably mirror or predict the progression or amelioration of CA will also be needed. Methods: The NIH-funded CA Biomarkers Network is a multidisciplinary group interested in the development and validation of CA biomarkers. This review summarizes our efforts to characterize and classify CA biomarkers. Results: We propose the "BIPED" biomarker classification (which stands for Burden of Disease, Investigative, Prognostic, Efficacy of Intervention and Diagnostic), and offer suggestions on optimal study design and analytic methods for use in CA investigations. Conclusion. The BIPED classification provides specific biomarker definitions with the goal of improving our ability to develop and analyze OA biomarkers, and to communicate these advances within a common framework. (C) 2006 OsteoArthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

By the author/editor: Bauer, D. C.; Hunter, D. J.; Abramson, S. B.; Attur, M.; Corr, M.; Felson, D.; show more...; Heinegård, Dick; Jordan, J. M.; Kepler, T. B.; Lane, N. E.; Saxne, Tore; Tyree, B.; Kraus, V. B.; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Rheumatology and ...

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.