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Radiation treatment...
Radiation treatment monitoring using multimodal functional imaging: PET/CT ((18)F-Fluoromisonidazole & (18)F-Fluorocholine) and DCE-US.
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Arteaga-Marrero, Natalia (author)
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Brekke Rygh, Cecilie (author)
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Mainou-Gomez, Jose F (author)
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Adamsen, Tom C H (author)
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- Lutay, Nataliya (author)
- Lund University,Lunds universitet,Dermatologi och venereologi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Avdelningen för medicinsk mikrobiologi,Institutionen för laboratoriemedicin,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Dermatology and Venereology (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Division of Medical Microbiology,Department of Laboratory Medicine,Division of Microbiology, Immunology and Glycobiology - MIG
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Reed, Rolf K (author)
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Olsen, Dag R (author)
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(creator_code:org_t)
- 2015-12-18
- 2015
- English.
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In: Journal of Translational Medicine. - : Springer Science and Business Media LLC. - 1479-5876. ; 13
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Abstract
Subject headings
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- This study aims to assess the effect of radiation treatment on the tumour vasculature and its downstream effects on hypoxia and choline metabolism using a multimodal approach in the murine prostate tumour model CWR22. Functional parameters derived from Positron Emission Tomography (PET)/Computer Tomography (CT) with (18)F-Fluoromisonidazole ((18)F-FMISO) and (18)F-Fluorocholine ((18)F-FCH) as well as Dynamic Contrast-Enhanced Ultrasound (DCE-US) were employed to determine the relationship between metabolic parameters and microvascular parameters that reflect the tumour microenvironment. Immunohistochemical analysis was employed for validation.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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