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Sökning: id:"swepub:oai:lup.lub.lu.se:b88a184e-2033-4f7b-9b4f-da416474aefb" > Oxytocin levels in ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003272naa a2200409 4500
001oai:lup.lub.lu.se:b88a184e-2033-4f7b-9b4f-da416474aefb
003SwePub
008160401s2007 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/6703642 URI
024a https://doi.org/10.1016/j.regpep.2006.10.0112 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Bakos, J.4 aut
2451 0a Oxytocin levels in the posterior pituitary and in the heart are modified by voluntary wheel running
264 1b Elsevier BV,c 2007
520 a We hypothesized that voluntary wheel running results in increased secretion of oxytocin, a peptide involved in the stress response. An additional hypothesis was that prolonged exercise affects oxytocin levels in the heart, which is in line with the potential role of oxytocin in cardiovascular functions. Voluntary wheel running lasted 3 weeks and daily running distances increased progressively reaching maximum levels about 8 km (Sprague-Dawley rats) and 4 km (Lewis strain). The exercise resulted in significant reduction of epididymal fat, slight increase in glucose transporter GLUT4 mRNA levels and significant enhancement of plasma density. Voluntary exercise failed to influence plasma oxytocin levels either in Lewis or Sprague-Dawley rats, but it resulted in a significant decrease of oxytocin concentrations in the posterior pituitary. Plasma oxytocin concentrations were not modified even if the measurements were made in the dark phase of the day. In voluntary wheel running Sprague-Dawley rats, the content of oxytocin in the right heart atrium was lower than in controls. Thus, the present findings demonstrate that prolonged voluntary wheel running results in a decrease in pituitary oxytocin content without evident changes in hormone concentrations in peripheral blood. However, prolonged exercise used has a significant impact on oxytocin levels in the heart. (c) 2006 Elsevier B.V. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng
653 a cardiovascular system
653 a exercise
653 a neuropeptide
653 a rat
700a Hlavacova, N.4 aut
700a Makatsori, A.4 aut
700a Tybitanclova, K.4 aut
700a Zorad, S.4 aut
700a Hinghofer-Szalkay, H.4 aut
700a Johansson, Barbrou Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)neur-bjo
700a Jezova, D.4 aut
710a Neurologi, Lundb Sektion IV4 org
773t Regulatory Peptidesd : Elsevier BVg 139:1-3, s. 96-101q 139:1-3<96-101x 1873-1686x 0167-0115
856u http://dx.doi.org/10.1016/j.regpep.2006.10.011y FULLTEXT
8564 8u https://lup.lub.lu.se/record/670364
8564 8u https://doi.org/10.1016/j.regpep.2006.10.011

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