id:"swepub:oai:lup.lub.lu.se:d8be20db-3ab7-4837-9b61-59250d728ad1"
Search: id:"swepub:oai:lup.lub.lu.se:d8be20db-3ab7-4837-9b61-59250d728ad1" > Distinct expression...
- 1 of 1
- Previous record
- Next record
- To hitlist
Distinct expression of calnexin in major human salivary glands
- Gassler, N (author)
-
- Bohn, Jörg (author)
- Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine
- Schnolzer, M (author)
- show more...
- Scheuerer, J (author)
- Obermuller, N (author)
- Otto, HF (author)
- Autschbach, F (author)
- show less...
- (creator_code:org_t)
- 2003
- 2003
- English.
- In: Histology and Histopathology. - 1699-5848. ; 18:1, s. 121-127
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Calnexin (Cnx) has been characterized as a membrane-bound protein that transiently interacts in a unique chaperone system with newly synthesized glycoproteins in order to allow the establishment of their proper tertiary and, in most cases, quarternary structures. The aim of the study was to identify and to locate the expression of Cnx in the three major salivary glands of humans by different methods. Strong expression of Cnx protein and mRNA were generally found in serous salivary secretory units. With regard to mucous secretory units, expression of Cnx was only detectable at a low level in mucous acinar cells of sublingual glands, but not of submandibular glands. Expression of Cnx was always preserved in the surface epithelium of intralobar and interlobular duct segments. In addition, expression of Cnx was detected in sebaceous glands of parotid tissues, with a distribution pattern resembling that seen in sebaceous glands of the normal skin. In conclusion, production of saliva is associated with the expression of Cnx. Synthesis of molecules in mucous secretory units is not necessarily associated with a strong Cnx expression, whereas synthesis in serous secretory units apparently is. The tissue-specific Cnx expression is also paralleled by the observation that the secretions produced by the major salivary glands differ in their composition and amount.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- calnexin
- salivary gland
- human
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
- Histology and Histopathology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Gassler, N
- Bohn, Jörg
- Schnolzer, M
- Scheuerer, J
- Obermuller, N
- Otto, HF
- show more...
- Autschbach, F
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Surgery
- Articles in the publication
- Histology and Hi ...
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
