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Long term oncologic...
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Ekdahl, LinneaLund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Livmoder och livmoderhalscancer,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Endometrial and cervical cancer,Lund University Research Groups,Skåne University Hospital
(författare)
Long term oncologic and reproductive outcomes after robot-assisted radical trachelectomy for early-stage cervical cancer. An international multicenter study
- Artikel/kapitelEngelska2022
Förlag, utgivningsår, omfång ...
Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:ee667989-b1bd-460f-b4e5-fd00d45d8852
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https://lup.lub.lu.se/record/ee667989-b1bd-460f-b4e5-fd00d45d8852URI
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https://doi.org/10.1016/j.ygyno.2021.12.029DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:149990230URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Objectives: Long term outcomes following fertility sparing robot-assisted radical trachelectomy (RRT). Methods: A retrospective study of consecutive women selected for RRT between 2007 and 2019 at five referral centres. Generally used selection criteria for fertility-sparing surgery were applied. Oncologic, reproductive and long-term clinical data were analysed. Results: Of the 166 included women, 149 completed a RRT. Median tumor size was 9 mm (range 3-20 mm), 111 women (75%) had FIGO 2009 stage IB1 cancer and 4.8% were node positive. At a median follow up of 58 months, 12 of all women (7.2%) and 9 of 149 women (6%) who underwent completed RRT with fertility preservation had recurred and two had died. 70 of 88 women (80%) who attempted to conceive succeeded, resulting in 81 pregnancies that progressed beyond the first trimester and 76 live births of which 54 (70%) were delivered at term and 65 (86%) delivered after gestational week 32. A short postoperative cervical length was associated with impaired fertility. A late secondary hysterectomy was necessary in four women due to persistent bleeding (n = 2), hematometra due to a cervical stenosis (n = 1) and recurrent dysplasia (n = 1). Conclusion: In this long-term follow-up of RRT the recurrence rate is comparable to larger individual studies of minimally invasive or vaginal radical trachelectomy with similar risk profile and follow up. The high pregnancy rate and low rate of premature delivery before 32 weeks GA may promote the use of robot-assisted approach.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Paraghamian, SarahUniversity of North Carolina
(författare)
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Eoh, Kyung JinYonsei University
(författare)
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Thumuluru, Kavitha MadhuriRoyal Surrey NHS Foundation Trust
(författare)
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Butler-Manuel, Simon A.Royal Surrey NHS Foundation Trust
(författare)
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Kim, Young TaeYonsei University
(författare)
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Boggess, John F.University of North Carolina
(författare)
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Persson, JanLund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Livmoder och livmoderhalscancer,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Endometrial and cervical cancer,Lund University Research Groups,Skåne University Hospital(Swepub:lu)gyn-jpe
(författare)
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Falconer, HenrikKarolinska Institutet,Karolinska University Hospital
(författare)
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Obstetrik och gynekologi, LundSektion V
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Gynecologic Oncology: Elsevier BV164:3, s. 529-5340090-82581095-6859
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