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Sökning: id:"swepub:oai:lup.lub.lu.se:f945df51-dd3e-4bc7-aa02-808d35dce740" > Prostate cancer sur...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004340naa a2200421 4500
001oai:lup.lub.lu.se:f945df51-dd3e-4bc7-aa02-808d35dce740
003SwePub
008181024s2018 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/f945df51-dd3e-4bc7-aa02-808d35dce7402 URI
024a https://doi.org/10.1002/cam4.17642 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Chattopadhyay, Subhayanu German Cancer Research Centre,Heidelberg University4 aut0 (Swepub:lu)su1252ch
2451 0a Prostate cancer survivors : Risk and mortality in second primary cancers
264 c 2018-10-01
264 1b Wiley,c 2018
520 a To assess etiological and clinical consequences of second primary cancers (SPCs) in prostate cancer (PC) patients, we followed newly diagnosed patients to identify men who were diagnosed with a SPC and recorded their causes of death. We used the Swedish Family-Cancer Database to assess relative risks (RRs) and causes of death in SPCs until the year 2015 in patients with a PC diagnosis between 2001 and 2010. Among a total of 4.26 million men, 76 614 were diagnosed with PC at the median age of 71 years. Among them, 8659 (11.3%) received a subsequent diagnosis of SPC after a median follow-up of 4 years. The most common SPCs were colorectal, skin, bladder, and lung cancers, melanoma, and non-Hodgkin lymphoma. The ranking was almost identical with first cancers among elderly men in Sweden. The RR for SPCs in prostate-specific antigen—detected PC was approximately equal to RR in other PC. Mortality patterns of PC patients were distinct depending on the presence or absence of SPC. Among patients with SPC, 47.8% died as a result of the corresponding SPC, followed by other causes (22.2%) and PC (18.1%). For patients without SPC, PC and non-neoplastic causes almost matched each other as the main causes of death (48.5% and 47.8%). The results suggest that SPCs appear autonomous from primary PC and reflect incidence and mortality of first cancers in general. SPC was the most common cause of death in patients with SPC; close to half of the patients died due to SPC. For improved survival in PC patients, prevention and early detection of SPCs would be important, and the present results suggest that risk factors for SPC in PC are the same as those for first cancer in general.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a incidence
653 a mortality
653 a multiple primary cancers
653 a relative risk
653 a screening
700a Zheng, Guoqiaou German Cancer Research Centre,Heidelberg University4 aut0 (Swepub:lu)gu4135zh
700a Hemminki, Ottou University of Helsinki,Helsinki University Central Hospital4 aut
700a Försti, Astau Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,German Cancer Research Centre4 aut0 (Swepub:lu)med-asf
700a Sundquist, Kristinau Lund University,Lunds universitet,Allmänmedicin, kardiovaskulär epidemiologi och levnadsvanor,Forskargrupper vid Lunds universitet,Family Medicine, Cardiovascular Epidemiology and Lifestyle,Lund University Research Groups,Shimane University,Icahn School of Medicine at Mount Sinai4 aut0 (Swepub:lu)med-ksq
700a Hemminki, Kariu Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,German Cancer Research Centre4 aut0 (Swepub:lu)med-khk
710a German Cancer Research Centreb Heidelberg University4 org
773t Cancer Medicined : Wileyg 7:11, s. 5752-5759q 7:11<5752-5759x 2045-7634
856u http://dx.doi.org/10.1002/cam4.1764x freey FULLTEXT
856u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.1764
8564 8u https://lup.lub.lu.se/record/f945df51-dd3e-4bc7-aa02-808d35dce740
8564 8u https://doi.org/10.1002/cam4.1764

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