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Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor
- Garcia, YR (author)
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- Pabon-Martinez, YV (author)
- Karolinska Institutet
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- Smith, CIE (author)
- Karolinska Institutet
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- Madder, A (author)
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- (creator_code:org_t)
- 2017
- 2017
- English.
- In: Chemical communications (Cambridge, England). - : Royal Society of Chemistry (RSC). - 1364-548X .- 1359-7345. ; 53:49, s. 6653-6656
- Journal article (peer-reviewed)
Abstract
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- We here report on the synthesis of the first mimic of the DNA binding domain of the c-Myc/Max-bHLH-ZIP transcription factor able to selectively recognize its cognate E-box sequence 5′-CACGTG-3′ through the major groove of the double-stranded DNA.
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